Evidence map›Paper›PMID 36676101›Full record

ReviewLife (Basel, Switzerland)2023

Gut Microbiome Composition in Patients with Chronic Urticaria: A Review of Current Evidence and Data.

Mirela Krišto, Liborija Lugović-Mihić, Melba Muñoz, Maja Rupnik, Aleksander Mahnic, Petar Ozretić, Morana Jaganjac, Diana Ćesić, Matea Kuna

Open access · goldAbstract readReview
In one paragraph

Review in Life (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
7.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 25 citations in OpenAlex.

  1. Review
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  15. Association of GutLife (Basel, Switzerland) · 2023
    Article
  16. Review
  17. Causal relationships among gut microbiota, blood metabolites, and urticaria in East Asians: A Mendelian randomization study.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 3 countries.

Mirela KrištoDepartment of Dermatovenereology, University Hospital Centre Sestre Milosrdnice, 10000 Zagreb, Croatia.ORCID 0000-0002-7945-1888
Liborija Lugović-MihićDepartment of Dermatovenereology, University Hospital Centre Sestre Milosrdnice, 10000 Zagreb, Croatia.ORCID 0000-0001-7494-5742
Melba MuñozInstitute of Allergology, Charité-Universitätsmedizin Berlin, Freie Universität Berlin, and Humboldt-Universität zu Berlin, 13125 Berlin, Germany.
Maja RupnikDepartment for Microbiological Research, National Laboratory for Health, Environment and Food, SI-2000 Maribor, Slovenia.ORCID 0000-0003-1930-3290
Aleksander MahnicDepartment for Microbiological Research, National Laboratory for Health, Environment and Food, SI-2000 Maribor, Slovenia.
Petar OzretićLaboratory for Hereditary Cancer, Division of Molecular Medicine, Ruđer Bošković Institute,10000 Zagreb, Croatia.ORCID 0000-0001-9757-6636
Morana JaganjacLaboratory for Oxidative Stress, Ruđer Bošković Institute, 10000 Zagreb, Croatia.ORCID 0000-0001-5051-1843
Diana ĆesićDepartment of Dermatovenereology, University Hospital Centre Sestre Milosrdnice, 10000 Zagreb, Croatia.
Matea KunaDepartment of Dermatovenereology, University Hospital Centre Sestre Milosrdnice, 10000 Zagreb, Croatia.ORCID 0000-0001-9932-5558
Ruđer Bošković Institute · HRHumboldt-Universität zu Berlin · DENational Laboratory of Health, Environment and Food · SIUniversity of Maribor · SI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent studies have linked gut microorganism composition and chronic urticaria (CU); however, the underlying mechanisms responsible for this connection are unknown. Since the human immune system is in homeostasis with microbiota, and the composition of the microbiome regulates the development and function of the immune system, it is likely that an alteration of microbiota components (a dysbiosis) could influence the course of chronic spontaneous urticaria (CSU), including disease severity, patient quality of life and treatment outcome. To date, several studies have identified changes in the gut microbiota composition of patients with CSU, though only a few have exhibited metabolic abnormalities associated with gut dysbiosis. The studies on CSU patients predominantly showed that the relative abundance of beneficial bacteria was decreased (

Indexed as

chronic spontaneous urticariadysbiosisgut microbiomeintestinal microbiome compositionmetabolome

Identifiers

PMID36676101
PMCPMC9860868
OpenAlexW4313500027

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.