Evidence map›Paper›PMID 36675940›Full record

ArticleJournal of fungi (Basel, Switzerland)2023

High Incidence of Candidemia in Critically Ill COVID-19 Patients Supported by Veno-Venous Extracorporeal Membrane Oxygenation: A Retrospective Study.

Francesco Alessandri, Giancarlo Ceccarelli, Giuseppe Migliara, Valentina Baccolini, Alessandro Russo, Carolina Marzuillo, Mariateresa Ceparano, Giovanni Giordano, Pierfrancesco Tozzi, Gioacchini Galardo and 5 more

Abstract read
In one paragraph

Article in Journal of fungi (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  9. SevereJournal of intensive medicine · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Francesco AlessandriIntensive Care Unit, Department of General, Specialistic Surgery Sapienza University, 00185 Rome, Italy.ORCID 0000-0003-3989-4964
Giancarlo CeccarelliAzienda Ospedaliero Universitaria Policlinico Umberto I, 00161 Rome, Italy.ORCID 0000-0001-5921-3180
Giuseppe MigliaraDepartment of Public Health and Infectious Diseases, Sapienza University, 00185 Rome, Italy.ORCID 0000-0002-4573-6025
Valentina BaccoliniDepartment of Public Health and Infectious Diseases, Sapienza University, 00185 Rome, Italy.ORCID 0000-0002-7873-7817
Alessandro RussoUnit of Infectious and Tropical Diseases, Department of Medical and Surgical Sciences, "Magna Graecia" University, 88100 Catanzaro, Italy.ORCID 0000-0003-3846-4620
Carolina MarzuilloDepartment of Public Health and Infectious Diseases, Sapienza University, 00185 Rome, Italy.ORCID 0000-0002-7299-5727
Mariateresa CeparanoDepartment of Public Health and Infectious Diseases, Sapienza University, 00185 Rome, Italy.
Giovanni GiordanoAzienda Ospedaliero Universitaria Policlinico Umberto I, 00161 Rome, Italy.
Pierfrancesco TozziAzienda Ospedaliero Universitaria Policlinico Umberto I, 00161 Rome, Italy.
Gioacchini GalardoAzienda Ospedaliero Universitaria Policlinico Umberto I, 00161 Rome, Italy.ORCID 0000-0001-5941-9947
Giammarco RaponiDepartment of Public Health and Infectious Diseases, Sapienza University, 00185 Rome, Italy.ORCID 0000-0002-9665-0811
Claudio MastroianniDepartment of Public Health and Infectious Diseases, Sapienza University, 00185 Rome, Italy.ORCID 0000-0002-1286-467X
Mario VendittiDepartment of Public Health and Infectious Diseases, Sapienza University, 00185 Rome, Italy.ORCID 0000-0003-2639-0281
Francesco PuglieseIntensive Care Unit, Department of General, Specialistic Surgery Sapienza University, 00185 Rome, Italy.ORCID 0000-0002-8076-1250
Gabriella d'EttorreDepartment of Public Health and Infectious Diseases, Sapienza University, 00185 Rome, Italy.ORCID 0000-0002-3571-5677

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe incidence of candidemia in severe COVID-19 patients (0.8-14%) is two- to ten-fold higher than in non-COVID-19 patients.

methodsThis retrospective analysis aimed to analyse the incidence of bloodstream infections (BSI) due to Candida in a cohort of COVID-19 patients supported with ECMO.

resultsAmong 138 intubated and ventilated patients hospitalized for ≥10 days in the intensive care unit of a teaching hospital, 45 (32.6%) patients received ECMO support, while 93 patients (67.4%) did not meet ECMO criteria and were considered the control group. In the ECMO group, 16 episodes of candidaemia were observed, while only 13 in patients of the control group (36.0% vs. 14.0%,

conclusionsThis study confirms that the incidence of candidemia was significantly higher in critically ill COVID-19 patients supported with VV-ECMO than in critically ill COVID patients who did not meet criteria for VV-ECMO.

Indexed as

candidaCOVID-19mycosisveno-venous ECMO

Identifiers

PMID36675940
PMCPMC9861971

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.