ReviewJournal of fungi (Basel, Switzerland)2023
Lichen Depsides and Tridepsides: Progress in Pharmacological Approaches.
Review in Journal of fungi (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 32 citations in OpenAlex.
- Lichen-Derived Bioactive Compounds in Diabetes and Cardiovascular Risk: Experimental Evidence, Mechanisms, and Translational Challenges.Biomedicines · 2026Review
- Novel Phenanthraquinone Derivative from Antarctic LichenACS omega · 2026Article
- Phytochemical Profiling and Antioxidant and Enzymatic Evaluation of Extracts from the Antarctic LichensMolecules (Basel, Switzerland) · 2026Article
- Phytochemical Profiling ofPlants (Basel, Switzerland) · 2026Article
- Unveiling Lichen's Hidden Arsenal Against Multidrug Resistance: A Systematic Review of Their Essential Oils, Volatile Compounds and Extracts with Antimicrobial Applications.Microorganisms · 2026Review
- Phytochemical Screening and Physicochemical Properties of Oil Extract ofInternational journal of molecular sciences · 2026Article
- Experimental and In Silico Studies to Unravel the Antioxidant and Antibacterial Properties of Lichen Metabolites fromAntioxidants (Basel, Switzerland) · 2025Article
- Biosourced Functional Hydroxybenzoate-Journal of the American Chemical Society · 2025Article
- A Biosynthetic and Taxonomic Atlas of the Global Lichen Holobiont.Environmental microbiology · 2025Article
- A Comprehensive Review on Chemical Structures and Bioactivities ofJournal of fungi (Basel, Switzerland) · 2025Review
- Article
- Biosynthesis of the C-Glycosylated Depside Arenicolin B.Chembiochem : a European journal of chemical biology · 2025Article
- Unassuming Lichens: Nature's Hidden Antimicrobial Warriors.International journal of molecular sciences · 2025Review
- Telomeric RNA quadruplexes as targets for cancer prevention: The therapeutic potential of agonodepsides.Journal, genetic engineering & biotechnology · 2025Article
- Antioxidant and Antidiabetic Potential of the Antarctic LichenAntioxidants (Basel, Switzerland) · 2025Article
- In Vitro Antimicrobial Activity of Volatile Compounds from the LichenMicroorganisms · 2024Article
- Gyrophoric Acid, a Secondary Metabolite of Lichens, Exhibits Antidepressant and Anxiolytic Activity In Vivo in Wistar Rats.International journal of molecular sciences · 2024Article
- It Is Not All about Alkaloids-Overlooked Secondary Constituents in Roots and Rhizomes ofPlants (Basel, Switzerland) · 2024Article
- Antioxidant and antidiabetic activity and phytoconstituents of lichen extracts with temperate and polar distribution.Frontiers in pharmacology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Depsides and tridepsides are secondary metabolites found in lichens. In the last 10 years, there has been a growing interest in the pharmacological activity of these compounds. This review aims to discuss the research findings related to the biological effects and mechanisms of action of lichen depsides and tridepsides. The most studied compound is atranorin, followed by gyrophoric acid, diffractaic acid, and lecanoric acid. Antioxidant, cytotoxic, and antimicrobial activities are among the most investigated activities, mainly in in vitro studies, with occasional in silico and in vivo studies. Clinical trials have not been conducted using depsides and tridepsides. Therefore, future research should focus on conducting more in vivo work and clinical trials, as well as on evaluating the other activities. Moreover, despite the significant increase in research work on the pharmacology of depsides and tridepsides, there are many of these compounds which have yet to be investigated (e.g., hiascic acid, lassalic acid, ovoic acid, crustinic acid, and hypothamnolic acid).
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.