Evidence map›Paper›PMID 36675901›Full record

ReviewJournal of fungi (Basel, Switzerland)2023

Joana Branco, Isabel M Miranda, Acácio G Rodrigues

Open access · goldAbstract readReview
In one paragraph

Review in Journal of fungi (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed
21.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

65 citing papers in PubMed, 109 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. The metabolic trap:Journal of medical microbiology · 2026
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. We Are Family: Comparative Study ofPathogens (Basel, Switzerland) · 2026
    Article
  11. Article
  12. Article
  13. Six-month surveillance ofFrontiers in cellular and infection microbiology · 2026
    Article
  14. Review
  15. Secretion of serine proteases by planktonic- and biofilm-growing cells of Candida parapsilosis.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025
    Article
  16. Changes in microbial communities during the spoilage of palm wine stored at room temperature.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025
    Article
  17. Fungal Prosthetic Joint Infection byAntibiotics (Basel, Switzerland) · 2025
    Article
  18. Genome sequences of six clinical isolates ofMicrobiology resource announcements · 2025
    Article
  19. Clinical impact of fluconazole-resistantFuture microbiology · 2025
    Review
  20. Antimicrobial agents and chemotherapy · 2025
    Article

5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Joana BrancoDivision of Microbiology, Department of Pathology, Faculty of Medicine, University of Porto, 4200-319 Porto, Portugal.ORCID 0000-0002-2104-3742
Isabel M MirandaCardiovascular Research & Development Centre-UnIC@RISE, Faculty of Medicine, University of Porto, 4200-450 Porto, Portugal.
Acácio G RodriguesDivision of Microbiology, Department of Pathology, Faculty of Medicine, University of Porto, 4200-319 Porto, Portugal.
Universidade do Porto · PT

Funding

Centre for Health Technology and Services Research UID/IC/4255/2020Fundação para a Ciência e Tecnologia SFRH/BD/135883/2018
6 · The paper itself

Abstract

Candida parapsilosis is the second most common Candida species isolated in Asia, Southern Europe, and Latin America and is often involved in invasive infections that seriously impact human health. This pathogen is part of the psilosis complex, which also includes Candida orthopsilosis and Candida metapsilosis. C. parapsilosis infections are particularly prevalent among neonates with low birth weights, individuals who are immunocompromised, and patients who require prolonged use of a central venous catheter or other indwelling devices, whose surfaces C. parapsilosis exhibits an enhanced capacity to adhere to and form biofilms. Despite this well-acknowledged prevalence, the biology of C. parapsilosis has not been as extensively explored as that of Candida albicans. In this paper, we describe the molecular mechanistic pathways of virulence in C. parapsilosis and show how they differ from those of C. albicans. We also describe the mode of action of antifungal drugs used for the treatment of Candida infections, namely, polyenes, echinocandins, and azoles, as well as the resistance mechanisms developed by C. parapsilosis to overcome them. Finally, we stress the importance of the ongoing search for species-specific features that may aid the development of effective control strategies and thus reduce the burden on patients and healthcare costs.

Indexed as

antifungal resistanceazolesbiofilm formationCandida parapsilosisCandida spp.echinocandinsfungal infectionshealthcare-related infectionspolyenesvirulence attributes

Identifiers

PMID36675901
PMCPMC9862255
OpenAlexW4313575814

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.