ArticleJournal of personalized medicine2023
Epidemiology and Risk Factors of UTIs in Children-A Single-Center Observation.
Article in Journal of personalized medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.
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Who cites it
24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 45 citations in OpenAlex.
- Prevalence and determinants of urinary tract infection among Ethiopian children: a systematic review and meta-analysis of institution-based studies.BMC infectious diseases · 2026Pooled it
- Shorter versus longer-course of antibiotic therapy for urinary tract infections in pediatric population: an updated meta-analysis.European journal of pediatrics · 2024Pooled it
- Urinary tract infections in children.Nature reviews. Urology · 2026Review
- Diagnostic yield of urinary tract ultrasound in children following a first urinary tract infection: a retrospective cohort study.Pediatric radiology · 2026Article
- Prevalence and Clinical Features of Vesicoureteral Reflux in Children With Recurrent Urinary Tract Infections: A Cross-Sectional Study.Health science reports · 2026Article
- Urinary Tract Infections in Children - Microbiological Challenges and Mechanisms of Bacterial Resistance.Maedica · 2026Review
- Urobiota analysis and genome-wide association study in pediatric recurrent urinary tract infections and vesicoureteral reflux.JCI insight · 2026Article
- Prevalence and Antibiotic Resistance Pattern ofInfection and drug resistance · 2026Article
- Bacteriological Profile and Antibiotic Resistance Patterns of Uropathogenic Bacteria at HPGRB.Infection and drug resistance · 2026Article
- Diagnostic tests for urinary tract infections and antimicrobial resistance-a reality check between diagnostic innovation and implementation: a critical narrative review.Frontiers in cellular and infection microbiology · 2026Review
- Temporal trends and geographical variations in pediatric urinary tract infections: a comprehensive analysis using the global burden of disease study 2021.Tropical medicine and health · 2025Article
- Article
- Trends in Positive Urine Culture Rates and Antimicrobial Resistance in Non-Hospitalized Children from Western Romania: A Retrospective Observational Study.Antibiotics (Basel, Switzerland) · 2025Article
- The Role of Vitamins in Pediatric Urinary Tract Infection: Mechanisms and Integrative Strategies.Biomolecules · 2025Review
- A Systematic Review of the Accuracy and Reliability of Pyuria in Diagnosing Pediatric Urinary Tract Infections.Cureus · 2025Review
- Role of Gut and Urinary Microbiome in Children with Urinary Tract Infections: A Systematic Review.Diagnostics (Basel, Switzerland) · 2025Review
- Association between vitamin D levels and urinary tract infections.Caspian journal of internal medicine · 2025Article
- Machine learning model for predicting urinary tract infection risk in febrile children under 3 years of age.Frontiers in pediatrics · 2025Article
- Investigating the interaction of zno nanoparticles with flagellum and fimbriae in multi-drug resistant uropathogenic bacteria encoding fli and fim genes.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2024Article
- Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Urinary tract infections (UTIs) are one of childhood’s most common bacterial infections. The study aimed to determine the clinical symptoms, laboratory tests, risk factors, and etiology of different UTIs in children admitted to pediatric hospitals for three years. Methods: Patients with positive urine cultures diagnosed with acute pyelonephritis (APN) or cystitis (CYS) were analyzed for clinical symptoms, laboratory tests, risk factors, and etiology, depending on their age and sex. Results: We studied 948 children with UTIs (531 girls and 417 boys), with a median age of 12 (IQR 5−48 months). A total of 789 children had clinical symptoms; the main symptom was fever (63.4% of patients). Specific symptoms of UTIs were presented only in 16.3% of patients. Children with APN had shown significantly more frequent loss of appetite, vomiting, lethargy, seizures, and less frequent dysuria and haematuria than children with CYS. We found significantly higher median WBC, CRP, and leukocyturia in children with APN than with CYS. The risk factors of UTIs were presented in 46.6% of patients, of which 35.6% were children with APN and 61.7% with CYS. The main risk factor was CAKUT, more frequently diagnosed in children with CYS than APN, mainly in children <2 years. The most commonly isolated bacteria were Escherichia coli (74%). There was a higher percentage of urine samples with E. coli in girls than in boys. Other bacteria found were Klebsiella species, Pseudomonas aeruginosa, Proteus mirabilis, and Enterococcus species. Conclusions: Patients with APN were younger and had higher inflammatory markers. Often, fever is the only symptom of UTI in children, and other clinical signs are usually non-specific. The most common UTI etiology is E. coli, regardless of the clinical presentation and risk factors.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.