Evidence map›Paper›PMID 36675606›Full record

ArticleJournal of clinical medicine2023

Psychiatric Comorbidities in Children and Adolescents with High-Functioning Autism Spectrum Disorder: A Study on Prevalence, Distribution and Clinical Features in an Italian Sample.

Elisa Fucà, Silvia Guerrera, Giovanni Valeri, Laura Casula, Roberta Lucia Novello, Deny Menghini, Stefano Vicari

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 28 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Elisa FucàChild and Adolescent Neuropsychiatry Unit, Bambino Gesù Children's Hospital (IRCCS), 00146 Rome, Italy.ORCID 0000-0002-8795-7424
Silvia GuerreraChild and Adolescent Neuropsychiatry Unit, Bambino Gesù Children's Hospital (IRCCS), 00146 Rome, Italy.
Giovanni ValeriChild and Adolescent Neuropsychiatry Unit, Bambino Gesù Children's Hospital (IRCCS), 00146 Rome, Italy.
Laura CasulaChild and Adolescent Neuropsychiatry Unit, Bambino Gesù Children's Hospital (IRCCS), 00146 Rome, Italy.
Roberta Lucia NovelloChild and Adolescent Neuropsychiatry Unit, Bambino Gesù Children's Hospital (IRCCS), 00146 Rome, Italy.
Deny MenghiniChild and Adolescent Neuropsychiatry Unit, Bambino Gesù Children's Hospital (IRCCS), 00146 Rome, Italy.ORCID 0000-0002-3459-2601
Stefano VicariChild and Adolescent Neuropsychiatry Unit, Bambino Gesù Children's Hospital (IRCCS), 00146 Rome, Italy.
Bambino Gesù Children's Hospital · ITUniversità Cattolica del Sacro Cuore · IT

Funding

Ministero della Salute Current Reserach
6 · The paper itself

Abstract

This study investigated the prevalence and distribution of psychiatric comorbidities in a group of 472 children and adolescents with ASD aged 3-18 years. We examined differences in age, sex, IQ, adaptive skills, and ASD symptom severity by comparing participants with ASD (ASD group) with participants with ASD and a psychiatric disorder (ASD/PSY group). Overall, 32.2% of participants had a comorbid psychiatric condition. Attention deficit/hyperactivity disorder (ADHD) was the most frequent diagnosis among preschoolers (20.4%); among school-age children, ADHD and anxiety/obsessive-compulsive disorders were the most frequent conditions (21% and 10.6%, respectively); finally, adolescents exhibit higher prevalence of anxiety/obsessive-compulsive disorders (21.8%). The ASD/PSY group showed a higher percentage of males, they were older and showed lower adaptive skills than the group with ASD; moreover, their mothers exhibited higher stress levels than mothers of participants in the ASD group. The comparison between age groups in participants within ASD/PSY group revealed that preschoolers had lower IQ than school-age children and adolescents, and worse adaptive skills, more repetitive behaviors, and restricted interests than adolescents. This study highlights the importance of an accurate diagnosis of psychiatric comorbidities in children and adolescents with ASD, also considering individual and family impairment.

Indexed as

adaptive skillsbehavioral problemsemotional problemsgenderneurodevelopmental disorderspsychiatric disorders

Identifiers

PMID36675606
PMCPMC9864301
OpenAlexW4316664299

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.