Evidence map›Paper›PMID 36675585›Full record

ArticleJournal of clinical medicine2023

Depression, Anxiety, and Stress in Kazakhstani Women with Recurrent Pregnancy Loss: A Case-Control Study.

Assylzhan Issakhanova, Alpamys Issanov, Talshyn Ukybassova, Lyazzat Kaldygulova, Aizada Marat, Balkenzhe Imankulova, Nazira Kamzayeva, Wassim Y Almawi, Gulzhanat Aimagambetova

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Women's Experiences of Psychosocial Support after Recurrent Miscarriage: A Qualitative Content Analysis.International journal of community based nursing and midwifery · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 3 countries.

Assylzhan IssakhanovaSchool of Medicine, Nazarbayev University, Astana 010000, Kazakhstan.
Alpamys IssanovDepartment of Medicine, School of Medicine, Nazarbayev University, Astana 010000, Kazakhstan.ORCID 0000-0002-8968-2655
Talshyn UkybassovaClinical Academic Department of Women's Health, Corporate Fund "University Medical Center", Astana 010000, Kazakhstan.
Lyazzat KaldygulovaDepartment of Obstetrics and Gynecology #2, West-Kazakhstan Marat Ospanov Medical University, Aktobe 030012, Kazakhstan.
Aizada MaratDepartment of Obstetrics and Gynecology #1, NJSC "Astana Medical University", Astana 010000, Kazakhstan.
Balkenzhe ImankulovaClinical Academic Department of Women's Health, Corporate Fund "University Medical Center", Astana 010000, Kazakhstan.
Nazira KamzayevaClinical Academic Department of Women's Health, Corporate Fund "University Medical Center", Astana 010000, Kazakhstan.
Wassim Y AlmawiDepartment of Biomedical Sciences, School of Medicine, Nazarbayev University, Astana 010000, Kazakhstan.ORCID 0000-0003-1633-9757
Gulzhanat AimagambetovaDepartment of Biomedical Sciences, School of Medicine, Nazarbayev University, Astana 010000, Kazakhstan.ORCID 0000-0002-2868-4497
National Research Center for Maternal and Child Health · KZNazarbayev University · KZAstana Medical University · KZTunis University · TNUniversity of British Columbia · CAWest Kazakhstan Marat Ospanov State Medical University · KZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Recurrent pregnancy loss (RPL) is associated with increased incidence and severity of depression, anxiety, and stress, and screening for these comorbidities following miscarriages is beneficial for women with RPL who are planning future pregnancies. This study aims to investigate depression, anxiety, and stress among Kazakhstani women with RPL. Methods: This was a case−control study involving 70 women with confirmed RPL and 78 ethnically matched control women. Depression, anxiety, and stress were evaluated using the Depression Anxiety Stress Scales (DASS)-21 instrument. Linear regression and correlation analysis were used in assessing the association of RPL with symptoms of depression, and/or anxiety, and/or stress, after adjusting for key covariates. Results: Women with RPL were found to have significantly higher mean scores for depression (p < 0.001), anxiety (p < 0.001), and stress (p < 0.001) symptoms. Mild−moderate stress and mild−moderate and severe−extreme depression and anxiety symptoms were more frequent in the RPL group than in the control group. Regression analysis demonstrated that RPL was the only significant variable associated with anxiety, depression, and stress symptoms. Conclusion: The results of this study suggest that women with RPL are more likely to experience heightened symptoms of depression, anxiety, and stress. Proper psychological counseling is recommended for women with RPL, as well as their spouses.

Indexed as

anxietydepressionKazakhstanrecurrent pregnancy lossstress

Identifiers

PMID36675585
PMCPMC9863265
OpenAlexW4316467403

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.