Evidence map›Paper›PMID 36675485›Full record

ArticleJournal of clinical medicine2023

The Burden of Non-Alcoholic Fatty Liver Disease in Adolescents with Polycystic Ovary Syndrome: A Case-Control Study.

Aikaterini Giannouli, Vasiliki Efthymiou, Marianna Konidari, Iliana Mani, Leon Aravantinos, Spyridon P Dourakis, Aristeidis Antoniou, Efthymios Deligeoroglou, Flora Bacopoulou

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
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  11. Therapeutic Effect ofClinical medicine insights. Endocrinology and diabetes · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Aikaterini GiannouliCenter for Adolescent Medicine and UNESCO Chair in Adolescent Health Care, First Department of Pediatrics, Medical School, National and Kapodistrian University of Athens, Aghia Sophia Children's Hospital, 1 Thivon Str., 11527 Athens, Greece.ORCID 0000-0002-3146-9384
Vasiliki EfthymiouCenter for Adolescent Medicine and UNESCO Chair in Adolescent Health Care, First Department of Pediatrics, Medical School, National and Kapodistrian University of Athens, Aghia Sophia Children's Hospital, 1 Thivon Str., 11527 Athens, Greece.ORCID 0000-0002-3320-6588
Marianna KonidariFirst Department of Radiology, Medical School, National and Kapodistrian University of Athens, Aretaieio Hospital, 76 Vassilisis Sofias Ave., 11528 Athens, Greece.ORCID 0000-0003-2678-0845
Iliana ManiResearch Laboratory, Second Department of Internal Medicine, Medical School, National and Kapodistrian University of Athens, Hippokratio Hospital, 11527 Athens, Greece.
Leon AravantinosSecond Department of Obstetrics and Gynecology, Medical School, National and Kapodistrian University of Athens, Aretaieio Hospital, 76 Vassilisis Sofias Ave., 11528 Athens, Greece.
Spyridon P DourakisResearch Laboratory, Second Department of Internal Medicine, Medical School, National and Kapodistrian University of Athens, Hippokratio Hospital, 11527 Athens, Greece.
Aristeidis AntoniouFirst Department of Radiology, Medical School, National and Kapodistrian University of Athens, Aretaieio Hospital, 76 Vassilisis Sofias Ave., 11528 Athens, Greece.
Efthymios DeligeoroglouDepartment of Pediatric & Adolescent Gynecology, Mitera Children's Hospital, Erythrou Stavrou, 15123 Athens, Greece.
Flora BacopoulouCenter for Adolescent Medicine and UNESCO Chair in Adolescent Health Care, First Department of Pediatrics, Medical School, National and Kapodistrian University of Athens, Aghia Sophia Children's Hospital, 1 Thivon Str., 11527 Athens, Greece.ORCID 0000-0003-1001-0926
National and Kapodistrian University of Athens · GRUNESCO · FRMitera Hospital · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this case-control study was to assess the burden of non-alcoholic fatty liver disease (NAFLD) in adolescents with polycystic ovary syndrome (PCOS) and its associations with insulin resistance, hyperandrogenism, and other metabolic characteristics of the syndrome. A total of 87 Caucasian adolescent girls (47 with PCOS and 40 controls), aged 12.3-20.4 years, underwent blood sampling for glucose metabolism, hormonal and lipid profile, gynecological and liver ultrasound, and liver elastography. Indices of insulin resistance, liver steatosis, and liver fibrosis were calculated. NAFLD diagnosed by ultrasound was more prevalent in adolescents with PCOS than controls (22.7% vs. 6.1%,

Indexed as

adolescentfatty liverinsulin resistanceliver steatosisMAFLDNAFLDnon-alcoholic fatty liver diseaseobesityPCOSpolycystic ovary syndrome

Identifiers

PMID36675485
PMCPMC9860755
OpenAlexW4315573386

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.