Evidence map›Paper›PMID 36675449›Full record

ArticleJournal of clinical medicine2023

Handheld Ultrasound or Conventional Ultrasound Devices in Patients Undergoing HCT: A Validation Study.

Andrea Duminuco, Alessandra Cupri, Rosario Massimino, Salvatore Leotta, Giulio Antonio Milone, Bruno Garibaldi, Giulia Giuffrida, Orazio Garretto, Giuseppe Milone

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Andrea DuminucoUnità di Trapianto Emopoietico, Divisione di Ematologia, Azienda Ospedaliera Policlinico "G.Rodolico-San Marco", 95123 Catania, Italy.ORCID 0000-0002-9510-4755
Alessandra CupriUnità di Trapianto Emopoietico, Divisione di Ematologia, Azienda Ospedaliera Policlinico "G.Rodolico-San Marco", 95123 Catania, Italy.
Rosario MassiminoRadiologia CAST Azienda Ospedaliera Policlinico "G.Rodolico-San Marco", 95123 Catania, Italy.
Salvatore LeottaUnità di Trapianto Emopoietico, Divisione di Ematologia, Azienda Ospedaliera Policlinico "G.Rodolico-San Marco", 95123 Catania, Italy.ORCID 0000-0002-5465-5155
Giulio Antonio MiloneIstituto Oncologico del Mediterraneo, Unità di Trapianto Emopoietico, Divisione di Ematologia, 95029 Viagrande, Italy.
Bruno GaribaldiUnità di Trapianto Emopoietico, Divisione di Ematologia, Azienda Ospedaliera Policlinico "G.Rodolico-San Marco", 95123 Catania, Italy.ORCID 0000-0001-7540-805X
Giulia GiuffridaUnità di Trapianto Emopoietico, Divisione di Ematologia, Azienda Ospedaliera Policlinico "G.Rodolico-San Marco", 95123 Catania, Italy.
Orazio GarrettoRadiologia CAST Azienda Ospedaliera Policlinico "G.Rodolico-San Marco", 95123 Catania, Italy.
Giuseppe MiloneUnità di Trapianto Emopoietico, Divisione di Ematologia, Azienda Ospedaliera Policlinico "G.Rodolico-San Marco", 95123 Catania, Italy.ORCID 0000-0002-7840-4414
Policlinico Universitario di Catania · IT

Funding

Jazz Foundation of America Educational Grant - MEGS-OTH-7056
6 · The paper itself

Abstract

Abdominal ultrasound exams play a major role in the diagnosis of sinusoidal obstruction syndrome/veno-occlusive disease (SOS/VOD). The development of portable hand-held ultrasound devices (HHUS) has been shown to facilitate the diagnosis of many diseases, but little data on the value of HHUS in the diagnosis of SOS/VOD are available. We performed a study aimed at validating portable ultrasound (US) devices in the setting of hematopoietic stem cell transplant (HCT). Sixteen evaluable patients undergoing allogeneic HCT were studied using conventional US and HHUS during the first 3 weeks after transplant. The results obtained demonstrate that there is a close correlation between conventional and handheld ultrasound examination in the measurement of the right hepatic lobe (r = 0.912, p < 0.0001), the left hepatic lobe (r = 0.843, p < 0.0001), the portal vein (PV) (r = 0.724, p < 0.0001), and the spleen (r = 0.983, p < 0.0001) based on Pearson’s correlation. The same data, analyzed through Lin’s concordance correlation coefficient, evidenced a substantial level of agreement in the comparison of the spleen and right hepatic lobe, while a lower grade of agreement in the measurement of the portal vein and left hepatic lobe. Moreover, there was good agreement between results obtained by the two types of ultrasound devices in assessing ascites (p < 0.0001), gallbladder thickening (p < 0.0001), and the direction of PV flow (p < 0.0001). HHUS device allows the study of HokUs-10 parameters with an excellent agreement with conventional US, and may contribute to SOS/VOD diagnosis.

Indexed as

handheld ultrasound devicehematopoietic stem cell transplantationliver veno-occlusive disease

Identifiers

PMID36675449
PMCPMC9867323
OpenAlexW4313894355

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.