Evidence map›Paper›PMID 36675438›Full record

ArticleJournal of clinical medicine2023

Anatomical Variations of the Human Cochlea Using an Image Analysis Tool.

Raabid Hussain, Attila Frater, Roger Calixto, Chadlia Karoui, Jan Margeta, Zihao Wang, Michel Hoen, Herve Delingette, François Patou, Charles Raffaelli and 2 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Scala vestibuli cochlear implantation: exploring feasibility and outcomes- a systematic review.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
    Pooled it
  2. Article
  3. Cochlear integrity and scalar translocation assessment after cochlear implantation based on three-dimensional anatomical reconstructions.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 3 countries.

Raabid HussainResearch & Technology, Oticon Medical, 06220 Vallauris, France.ORCID 0000-0001-7831-3267
Attila FraterResearch & Technology, Oticon Medical, 06220 Vallauris, France.
Roger CalixtoResearch & Technology, Oticon Medical, 06220 Vallauris, France.
Chadlia KarouiClinical Evidence Department, Oticon Medical, 06220 Vallauris, France.ORCID 0000-0003-4661-1731
Jan MargetaResearch and Development, KardioMe, 01851 Nova Dubnica, Slovakia.ORCID 0000-0003-4882-0502
Zihao WangEpione Team, Inria, Université Côte d'Azur, 06902 Sophia Antipolis, France.
Michel HoenClinical Evidence Department, Oticon Medical, 06220 Vallauris, France.ORCID 0000-0003-2099-8130
Herve DelingetteEpione Team, Inria, Université Côte d'Azur, 06902 Sophia Antipolis, France.
François PatouResearch & Technology, Oticon Medical, 06220 Vallauris, France.ORCID 0000-0002-4872-9314
Charles RaffaelliInstitut Universitaire de la Face et du Cou, Nice, Centre Hospitalier Universitaire de Nice, Université Côte d'Azur, 06100 Nice, France.
Clair VandersteenInstitut Universitaire de la Face et du Cou, Nice, Centre Hospitalier Universitaire de Nice, Université Côte d'Azur, 06100 Nice, France.ORCID 0000-0001-5597-2040
Nicolas GuevaraInstitut Universitaire de la Face et du Cou, Nice, Centre Hospitalier Universitaire de Nice, Université Côte d'Azur, 06100 Nice, France.ORCID 0000-0002-4286-6465
Oticon Medical (Denmark) · DKUniversité Côte d'Azur · FRInstitut national de recherche en sciences et technologies du numérique · FRNES (Slovakia) · SK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Understanding cochlear anatomy is crucial for developing less traumatic electrode arrays and insertion guidance for cochlear implantation. The human cochlea shows considerable variability in size and morphology. This study analyses 1000+ clinical temporal bone CT images using a web-based image analysis tool. Cochlear size and shape parameters were obtained to determine population statistics and perform regression and correlation analysis. The analysis revealed that cochlear morphology follows Gaussian distribution, while cochlear dimensions A and B are not well-correlated to each other. Additionally, dimension B is more correlated to duct lengths, the wrapping factor and volume than dimension A. The scala tympani size varies considerably among the population, with the size generally decreasing along insertion depth with dimensional jumps through the trajectory. The mean scala tympani radius was 0.32 mm near the 720° insertion angle. Inter-individual variability was four times that of intra-individual variation. On average, the dimensions of both ears are similar. However, statistically significant differences in clinical dimensions were observed between ears of the same patient, suggesting that size and shape are not the same. Harnessing deep learning-based, automated image analysis tools, our results yielded important insights into cochlear morphology and implant development, helping to reduce insertion trauma and preserving residual hearing.

Indexed as

cochlear implantationcochlear morphologystatistical analysis

Identifiers

PMID36675438
PMCPMC9867191
OpenAlexW4313894318

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.