Evidence map›Paper›PMID 36675422›Full record

ArticleJournal of clinical medicine2023

Association of the Cumulative Live Birth Rate with the Factors in Assisted Reproductive Technology: A Retrospective Study of 16,583 Women.

Qiumin Wang, Dan Qi, Lixia Zhang, Jingru Wang, Yanbo Du, Hong Lv, Lei Yan

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Qiumin WangCenter for Reproductive Medicine, Shandong University, Jinan 250012, China.ORCID 0000-0001-6560-1198
Dan QiCenter for Reproductive Medicine, Shandong University, Jinan 250012, China.
Lixia ZhangCenter for Reproductive Medicine, Shandong University, Jinan 250012, China.
Jingru WangCenter for Reproductive Medicine, Shandong University, Jinan 250012, China.
Yanbo DuCenter for Reproductive Medicine, Shandong University, Jinan 250012, China.ORCID 0000-0002-9912-8869
Hong LvCenter for Reproductive Medicine, Shandong University, Jinan 250012, China.
Lei YanCenter for Reproductive Medicine, Shandong University, Jinan 250012, China.
Shandong University · CN

Funding

the National Natural Science Foundation of China 82071617the Shandong Provincial Key Research and Development Program 2020ZLYS02the Shandong Provincial Medical and Health Science and Technology Development Program 2019WS171the Shandong Provincial Natural Science Foundation ZR2020MH072
6 · The paper itself

Abstract

The cumulative live birth rate (CLBR) can better reflect the overall treatment effect by successive treatments, and continuous rather than categorical variables as exposure variables can increase the statistical power in detecting the potential correlation. Therefore, the dose-response relationships might find an optimal dose for the better CLBR, offering evidence-based references for clinicians. To determine the dose-response relationships of the factors and the optimal ranges of the factors in assisted reproductive technology (ART) associated with a higher CLBR, this study retrospectively analyzed 16,583 patients undergoing the first in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) from January 2017 to January 2019. Our study demonstrated the optimal ranges of age with a higher CLBR were under 32.10 years. We estimated the CLBR tends to increase with increased levels of AMH at AMH levels below 1.482 ng/mL, and the CLBR reaches a slightly high level at AMH levels in the range from 2.58-4.18 ng/mL. The optimal ranges of basal FSH with a higher CLBR were less than 9.13 IU. When the number of cryopreserved embryos was above 1.055 and the number of total transferred embryos was 2, the CLBR was significantly higher. In conclusion, there is a non-linear dose-response relationship between the CLBR with age, AMH, basal FSH, and the number of cryopreserved embryos and total transferred embryos. We proposed the optimal ranges of the five factors that were correlated with a higher CLBR in the first oocyte retrieval cycle, which may help consultation at IVF clinics.

Indexed as

ageanti-Müllerian hormonecumulative live birthdose–response relationshipfollicle-stimulating hormonetransferred embryos

Identifiers

PMID36675422
PMCPMC9862593
OpenAlexW4313889651

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.