Evidence map›Paper›PMID 36675387›Full record

ArticleJournal of clinical medicine2023

Clinical Impact of Recipient-Derived Isoagglutinin Levels in ABO-Incompatible Hematopoietic Stem Cell Transplantation.

Minjeong Nam, Mina Hur, Hanah Kim, Tae-Hwan Lee, Gun-Hyuk Lee, Sumi Yoon, Seungman Park, Sung Yong Kim, Mark Hong Lee

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Minjeong NamDepartment of Laboratory Medicine, Korea University Anam Hospital, Seoul 02841, Republic of Korea.ORCID 0000-0003-3542-3487
Mina HurDepartment of Laboratory Medicine, Konkuk University School of Medicine, Seoul 05030, Republic of Korea.ORCID 0000-0002-4429-9978
Hanah KimDepartment of Laboratory Medicine, Konkuk University School of Medicine, Seoul 05030, Republic of Korea.ORCID 0000-0002-3266-638X
Tae-Hwan LeeDepartment of Laboratory Medicine, Konkuk University School of Medicine, Seoul 05030, Republic of Korea.
Gun-Hyuk LeeDepartment of Laboratory Medicine, Konkuk University School of Medicine, Seoul 05030, Republic of Korea.
Sumi YoonDepartment of Laboratory Medicine, Chung-Ang University College of Medicine, Seoul 06973, Republic of Korea.ORCID 0000-0001-7529-1613
Seungman ParkDepartment of Laboratory Medicine, National Cancer Center, Seoul 10408, Republic of Korea.
Sung Yong KimDivision of Hematology-Oncology, Department of Internal Medicine, Konkuk University School of Medicine, Seoul 05030, Republic of Korea.
Mark Hong LeeDivision of Hematology-Oncology, Department of Internal Medicine, Konkuk University School of Medicine, Seoul 05030, Republic of Korea.
Konkuk University · KRChung-Ang University · KRKorea University · KRNational Cancer Center · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

ABO incompatibility is not considered a contraindication for hematopoietic stem cell transplantation (HSCT). We hypothesized that recipient-derived isoagglutinin (RDI) levels could play a critical role in clinical outcomes. In this study, we compared clinical outcomes such as survival, GVHD, infection, relapse, transfusion, and engraftment, among ABO-compatible patients (ABOc), ABO-incompatible patients (ABOi) with low RDI, and ABOi patients with high RDI. The ABOi with high RDI group was defined as recipients with more than 1:16 RDI levels. We analyzed 103 recipients (ABOc, 53; ABOi with low RDI, 36; ABOi with high RDI, 14). The ABOi with high RDI group showed a decreased 1-year survival and increased acute GVHD grade IV and RBC transfusion (

Indexed as

graft-versus-host diseasehematopoietic stem cell transplantationplatelet engraftmentRBC transfusionrecipient-derived isoagglutininsurvival

Identifiers

PMID36675387
PMCPMC9866227
OpenAlexW4313648812

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.