Evidence map›Paper›PMID 36675303›Full record

ArticleInternational journal of molecular sciences2023

Neuroprotective Effects and Metabolomics Study of Protopanaxatriol (PPT) on Cerebral Ischemia/Reperfusion Injury In Vitro and In Vivo.

Fulin Wu, Sihan Lai, Dongxing Fu, Juntong Liu, Cuizhu Wang, Hao Feng, Jinping Liu, Zhuo Li, Pingya Li

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Fulin WuSchool of Pharmaceutical Sciences, Jilin University, Changchun 130021, China.
Sihan LaiSchool of Pharmaceutical Sciences, Jilin University, Changchun 130021, China.
Dongxing FuSchool of Pharmaceutical Sciences, Jilin University, Changchun 130021, China.
Juntong LiuSchool of Pharmaceutical Sciences, Jilin University, Changchun 130021, China.
Cuizhu WangSchool of Pharmaceutical Sciences, Jilin University, Changchun 130021, China.ORCID 0000-0002-0694-4059
Hao FengCollege of Basic Medicine Sciences, Jilin University, Changchun 130021, China.
Jinping LiuSchool of Pharmaceutical Sciences, Jilin University, Changchun 130021, China.ORCID 0000-0003-4020-879X
Zhuo LiSchool of Pharmaceutical Sciences, Jilin University, Changchun 130021, China.
Pingya LiSchool of Pharmaceutical Sciences, Jilin University, Changchun 130021, China.
Jilin University · CN

Funding

the projects of Jilin Provincial Department of Science and Technology 20200504006YYthe projects of Jilin Provincial Department of Science and Technology 20220204025YY
6 · The paper itself

Abstract

Stroke, one of the leading causes of disability and death worldwide, is a severe neurological disease that threatens human life. Protopanaxatriol (PPT), panaxatriol-type saponin aglycone, is a rare saponin that exists in

Indexed as

Brain IschemiaNeuroprotective AgentsReperfusion InjurySaponinsAnimalsGlucoseHumansInfarction, Middle Cerebral ArteryInterleukin-6RatsSapogeninsSuperoxide DismutaseTumor Necrosis Factor-alphaGlucoseInterleukin-6Neuroprotective AgentsprotopanaxatriolSapogeninsSaponinsSuperoxide DismutaseTumor Necrosis Factor-alphacerebral ischemia/reperfusionmetabolomicsneuroprotectiveprotopanaxatriol

Identifiers

PMID36675303
PMCPMC9861888
OpenAlexW4316672724

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.