Evidence map›Paper›PMID 36675119›Full record

ArticleInternational journal of molecular sciences2023

First Report of FARSA in the Regulation of Cell Cycle and Survival in Mantle Cell Lymphoma Cells via PI3K-AKT and FOXO1-RAG1 Axes.

Min Feng, Kun Yang, Jia Wang, Guilan Li, Han Zhang

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Min FengInstitute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Kunming 650118, China.
Kun YangInstitute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Kunming 650118, China.
Jia WangInstitute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Kunming 650118, China.
Guilan LiInstitute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Kunming 650118, China.
Han ZhangInstitute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Kunming 650118, China.ORCID 0000-0002-2684-512X
Chinese Academy of Medical Sciences & Peking Union Medical College · CNYunnan University · CN

Funding

Natural Science Foundation of Yunnan Province 2019FB089Program of Medical Discipline Leader in Yunnan Health System D-2019023Program of Medical Discipline Leader in Yunnan Health System D-2019027Technological Innovation Talents of Yunnan Province 2019HB044
6 · The paper itself

Abstract

Cancer-associated factors have been largely identified in the understanding of tumorigenesis and progression. However, aminoacyl-transfer RNA (tRNA) synthetases (aaRSs) have so far been neglected in cancer research due to their canonical activities in protein translation and synthesis. FARSA, the alpha subunit of the phenylalanyl-tRNA synthetase is elevated across many cancer types, but its function in mantle cell lymphoma (MCL) remains undetermined. Herein, we found the lowest levels of

Indexed as

Lymphoma, Mantle-CellAdultApoptosisCell CycleCell Line, TumorForkhead Box Protein O1Homeodomain ProteinsHumansPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktForkhead Box Protein O1FOXO1 protein, humanHomeodomain ProteinsPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktRAG-1 proteincell apoptosiscell cycleforkhead box O1mantle cell lymphomaphenylalanyl-tRNA synthetase subunit alpharegulatory network

Identifiers

PMID36675119
PMCPMC9865697
OpenAlexW4315864721

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.