Evidence map›Paper›PMID 36675115›Full record

ArticleInternational journal of molecular sciences2023

In Vivo Degradation Behavior of Magnesium Alloy for Bone Implants with Improving Biological Activity, Mechanical Properties, and Corrosion Resistance.

Shun-Yi Jian, Chiu-Feng Lin, Tung-Lin Tsai, Pei-Hua Wang, Chung-Hwan Chen, Sung-Yen Lin, Chun-Chieh Tseng

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 28 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Shun-Yi JianDepartment of Material Engineering, Ming Chi University of Technology, New Taipei City 24301, Taiwan.
Chiu-Feng LinDepartment of CEO, Metal Industries Research & Development Centre, Kaohsiung 802, Taiwan.
Tung-Lin TsaiCombination Medical Device Technology Division, Medical Devices R&D Service Department, Metal Industries Research & Development Centre, Kaohsiung 802, Taiwan.
Pei-Hua WangCombination Medical Device Technology Division, Medical Devices R&D Service Department, Metal Industries Research & Development Centre, Kaohsiung 802, Taiwan.
Chung-Hwan ChenDepartments of Orthopedics, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 80701, Taiwan.ORCID 0000-0001-8941-4792
Sung-Yen LinDepartments of Orthopedics, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 80701, Taiwan.ORCID 0000-0002-4191-2183
Chun-Chieh TsengCombination Medical Device Technology Division, Medical Devices R&D Service Department, Metal Industries Research & Development Centre, Kaohsiung 802, Taiwan.
Metal Industries Research & Development Centre · TWKaohsiung Medical University · TWMing Chi University of Technology · TWNational Sun Yat-sen University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to establish a surface modification technology for ZK60 magnesium alloy implants that can degrade uniformly over time and promote bone healing. It proposes a special micro-arc oxidation (MAO) treatment on ZK60 alloy that enables the composite electrolytes to create a coating with better corrosion resistance and solve the problems of uneven and excessive degradation. A magnesium alloy bone screw made in this way was able to promote the bone healing reaction after implantation in rabbits. Additionally, it was found that the MAO-treated samples could be sustained in simulated body-fluid solution, exhibiting excellent corrosion resistance and electrochemical stability. The Ca ions deposited in the MAO coating were not cytotoxic and were beneficial in enhancing bone healing after implantation.

Indexed as

Bone and BonesMagnesiumAlloysAnimalsCoated Materials, BiocompatibleCorrosionProstheses and ImplantsRabbitsAlloysCoated Materials, BiocompatibleMagnesiumbiodegradabilityEDTAIn-vitro testmicro-arc oxidationZK60 magnesium alloy

Identifiers

PMID36675115
PMCPMC9865414
OpenAlexW4316038015

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.