Evidence map›Paper›PMID 36674962›Full record

ArticleInternational journal of molecular sciences2023

Vertical Transmission and Antifungal Susceptibility Profile of Yeast Isolates from the Oral Cavity, Gut, and Breastmilk of Mother-Child Pairs in Early Life.

Maria João Azevedo, Ricardo Araujo, Joana Campos, Carla Campos, Ana Filipa Ferreira, Inês Falcão-Pires, Carla Ramalho, Egija Zaura, Eugénia Pinto, Benedita Sampaio-Maia

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Human microbiome acquisition and transmission.Nature reviews. Microbiology · 2025
    Review
  8. Review
  9. Article
  10. Article
  11. Microbiome variability and role ofJournal of oral microbiology · 2025
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Maria João AzevedoINEB-Instituto Nacional de Engenharia Biomédica, 4150-177 Porto, Portugal.ORCID 0000-0002-9117-4684
Ricardo AraujoINEB-Instituto Nacional de Engenharia Biomédica, 4150-177 Porto, Portugal.ORCID 0000-0001-7382-4834
Joana CamposINEB-Instituto Nacional de Engenharia Biomédica, 4150-177 Porto, Portugal.ORCID 0000-0002-4316-1520
Carla CamposServiço de Patologia Clínica, Departamento de Patologia e Medicina Laboratorial, Instituto Português de Oncologia do Porto Francisco Gentil, 4200-072 Porto, Portugal.
Ana Filipa FerreiraFaculdade de Medicina, Universidade do Porto, 4200-319 Porto, Portugal.
Inês Falcão-PiresFaculdade de Medicina, Universidade do Porto, 4200-319 Porto, Portugal.
Carla Ramalhoi3S-Instituto de Investigação e Inovação em Saúde, Universidade do Porto, 4200-135 Porto, Portugal.
Egija ZauraDepartment of Preventive Dentistry, Academic Center for Dentistry Amsterdam, University of Amsterdam and Vrije Universiteit Amsterdam, 1081 LA Amsterdam, The Netherlands.ORCID 0000-0003-1432-6194
Eugénia PintoFaculdade de Farmácia, Universidade do Porto, 4050-313 Porto, Portugal.ORCID 0000-0003-2948-5809
Benedita Sampaio-MaiaINEB-Instituto Nacional de Engenharia Biomédica, 4150-177 Porto, Portugal.ORCID 0000-0001-9368-8075
National Institute of Engineering, Technology and Innovation · PTUniversidade do Porto · PTAcademic Center for Dentistry Amsterdam · NLIPO Porto · PT

Funding

Biocodex (France) Biocodex National Call 2021 - PortugalEuropean Society of Clinical Microbiology and Infectious Diseases Research Grant 2021Fundação para a Ciência e Tecnologia UIDB/04423/2020, UIDP/04423/2020, SFRH/BD/144982/2019, CEECIND/01070/2018, POCI-01-0145-FEDER-029777/PTDC/MEC-MCI/29777/2017, SFRH/BD/138925/2018
6 · The paper itself

Abstract

Yeast acquisition begins at birth; however, the contribution of the mother on yeast transmission to the offspring and associated resistance is yet to be clarified. The aim of this study was to explore the vertical transmission of yeasts and their antifungal susceptibility profile in early life. Oral, fecal, and breastmilk samples were collected from 73 mother-child pairs four to twelve weeks after delivery and cultured on Sabouraud dextrose agar with chloramphenicol. The isolates were identified by MALDI-TOF MS. The vertical transmission was studied by microsatellite genotyping. Antifungal susceptibility was determined for fluconazole, voriconazole, miconazole, anidulafungin, and nystatin by broth microdilution assay, following CLSI-M60 guidelines. A total of 129 isolates were identified from 53% mother-child pairs. We verified the vertical transmission of

Indexed as

Antifungal AgentsMilk, HumanCandidaDrug Resistance, FungalHumansInfant, NewbornMicrobial Sensitivity TestsMother-Child RelationsMouthYeastsAntifungal Agentsantifungal susceptibilitymother–child fungal transmissionopportunistic/pathogenic fungi

Identifiers

PMID36674962
PMCPMC9867488
OpenAlexW4315640869

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.