Evidence map›Paper›PMID 36674918›Full record

ArticleInternational journal of molecular sciences2023

METTL3 Regulates Osteoclast Biological Behaviors via iNOS/NO-Mediated Mitochondrial Dysfunction in Inflammatory Conditions.

Di Li, Jinlin He, Caihong Fang, Yiwen Zhang, Mingli He, Zhanqi Zhang, Jinsong Hou, Qiong Xu

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 23 citations in OpenAlex.

  1. WTAP Transcriptional Suppression by KLF9 Drives Osteoclastogenesis via MAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  2. mMolecular medicine reports · 2026
    Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. METTL3-mediated mMolecular biology reports · 2025
    Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Di LiHospital of Stomatology, Sun Yat-sen University, Guangzhou 510055, China.
Jinlin HeHospital of Stomatology, Sun Yat-sen University, Guangzhou 510055, China.
Caihong FangHospital of Stomatology, Sun Yat-sen University, Guangzhou 510055, China.
Yiwen ZhangHospital of Stomatology, Sun Yat-sen University, Guangzhou 510055, China.
Mingli HeHospital of Stomatology, Sun Yat-sen University, Guangzhou 510055, China.
Zhanqi ZhangHospital of Stomatology, Sun Yat-sen University, Guangzhou 510055, China.
Jinsong HouHospital of Stomatology, Sun Yat-sen University, Guangzhou 510055, China.ORCID 0000-0001-5330-9528
Qiong XuHospital of Stomatology, Sun Yat-sen University, Guangzhou 510055, China.ORCID 0000-0002-7448-6723
Sun Yat-sen University · CN

Funding

Natural Science Foundation of Guangdong Province 2022A1515012179
6 · The paper itself

Abstract

Excessive differentiation of osteoclasts contributes to the disruption of bone homeostasis in inflammatory bone diseases. Methyltransferase-like 3 (METTL3), the core methyltransferase that installs an N6-methyladenosine (m

Indexed as

Bone ResorptionOsteoclastsAnimalsMethyltransferasesMiceNitric OxideRNA, MessengerMethyltransferasesMettl3 protein, mouseNitric OxideRNA, Messengerinducible nitric oxide synthase (iNOS)lipopolysaccharidem6Amitochondrial functionnitric oxide (NO)osteoclast

Identifiers

PMID36674918
PMCPMC9862541
OpenAlexW4315649130

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.