Evidence map›Paper›PMID 36674906›Full record

ArticleInternational journal of molecular sciences2023

Shape-Memory-Reduced Graphene/Chitosan Cryogels for Non-Compressible Wounds.

Hongyun Xuan, Qian Du, Ruimeng Li, Xiaoni Shen, Jiao Zhou, Biyun Li, Yan Jin, Huihua Yuan

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Extraction of Chitin from Black Soldier Fly (Life (Basel, Switzerland) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Hongyun XuanSchool of Life Science, Nantong University, Nantong 226019, China.
Qian DuSchool of Life Science, Nantong University, Nantong 226019, China.
Ruimeng LiSchool of Life Science, Nantong University, Nantong 226019, China.
Xiaoni ShenSchool of Life Science, Nantong University, Nantong 226019, China.
Jiao ZhouSchool of Life Science, Nantong University, Nantong 226019, China.
Biyun LiSchool of Life Science, Nantong University, Nantong 226019, China.
Yan JinSchool of Life Science, Nantong University, Nantong 226019, China.ORCID 0000-0003-4664-4787
Huihua YuanSchool of Life Science, Nantong University, Nantong 226019, China.ORCID 0000-0001-8657-984X
Nantong University · CN

Funding

National Natural Science Foundation of China 32000965 and 81801856
6 · The paper itself

Abstract

In this study, an antibacterial and shape-memory chitosan cryogel with high blood absorption and fast recovery from non-compressible wounds was prepared using a one-step method. Herein, we prepared a shape-memory-reduced graphene/chitosan (rGO-CTS) cryogel using a one-step method with a frozen mixing solution of chitosan, citric acid, dopamine, and graphene oxide, before treating it with alkaline solutions. The alkaline solution not only promoted the double cross-linking of chitosan but also induced dopamine to form polydopamine-reducing graphene oxide. Scanning electron microscope (SEM) images showed that the rGO-CTS cryogel possessed a uniform porous network structure, attributing excellent water-induced shape-memory properties. Moreover, the rGO-CTS cryogel exhibited good mechanical properties, antibacterial activity, and biocompatibility. In mouse liver trauma models, the rGO-CTS cryogel showed good blood clotting and hemostatic capabilities. Therefore, this composite cryogel has great potential as a new hemostatic material for application to non-compressible wounds.

Indexed as

ChitosanGraphiteHemostaticsAnimalsAnti-Bacterial AgentsCryogelsDisease Models, AnimalDopamineMiceAnti-Bacterial AgentsChitosanCryogelsDopaminegraphene oxideGraphiteHemostaticsantibacterialhemostaticone-step methodreduced graphene/chitosan cryogelshape memory

Identifiers

PMID36674906
PMCPMC9863902
OpenAlexW4315649528

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.