Evidence map›Paper›PMID 36674717›Full record

ArticleInternational journal of molecular sciences2023

Cysteamine/Cystamine Exert Anti-

Ivana Palucci, Alessandro Salustri, Flavio De Maio, Maria Del Carmen Pereyra Boza, Francesco Paglione, Michela Sali, Luca Occhigrossi, Manuela D'Eletto, Federica Rossin, Delia Goletti and 3 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Ivana PalucciDepartment of Laboratory Sciences and Infectious Diseases, Fondazione Policlinico Universitario "A. Gemelli", 00168 Rome, Italy.ORCID 0000-0003-2106-1761
Alessandro SalustriDipartimento di Scienze Biotecnologiche di Base, Cliniche Intensivologiche e Perioperatorie-Sezione di Microbiologia, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.
Flavio De MaioDepartment of Laboratory Sciences and Infectious Diseases, Fondazione Policlinico Universitario "A. Gemelli", 00168 Rome, Italy.ORCID 0000-0002-4744-9820
Maria Del Carmen Pereyra BozaDepartment of Laboratory Sciences and Infectious Diseases, Fondazione Policlinico Universitario "A. Gemelli", 00168 Rome, Italy.
Francesco PaglioneDepartment of Laboratory Sciences and Infectious Diseases, Fondazione Policlinico Universitario "A. Gemelli", 00168 Rome, Italy.
Michela SaliDepartment of Laboratory Sciences and Infectious Diseases, Fondazione Policlinico Universitario "A. Gemelli", 00168 Rome, Italy.
Luca OcchigrossiDipartimento di Biologia, Università degli Studi di Roma "Tor Vergata", 00173 Rome, Italy.ORCID 0000-0002-1674-7091
Manuela D'ElettoDipartimento di Biologia, Università degli Studi di Roma "Tor Vergata", 00173 Rome, Italy.
Federica RossinDipartimento di Biologia, Università degli Studi di Roma "Tor Vergata", 00173 Rome, Italy.ORCID 0000-0002-4313-8347
Delia GolettiDepartment of Epidemiology and Preclinical Research, National Institute for Infectious Diseases Translational Research Unit, IRCCS 'Lazzaro Spallanzani', 00149 Rome, Italy.ORCID 0000-0001-8360-4376
Maurizio SanguinettiDepartment of Laboratory Sciences and Infectious Diseases, Fondazione Policlinico Universitario "A. Gemelli", 00168 Rome, Italy.ORCID 0000-0002-9780-7059
Mauro PiacentiniDipartimento di Biologia, Università degli Studi di Roma "Tor Vergata", 00173 Rome, Italy.
Giovanni DeloguDipartimento di Scienze Biotecnologiche di Base, Cliniche Intensivologiche e Perioperatorie-Sezione di Microbiologia, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.
Università Cattolica del Sacro Cuore · ITUniversity of Rome Tor Vergata · ITAgostino Gemelli University Polyclinic · ITIstituto Nazionale per le Malattie Infettive Lazzaro Spallanzani · IT

Funding

Fondazione Fibrosi Cistica FFC#10/2018Fondazione Fibrosi Cistica FFC#4/2021National Institute for Infectious Diseases IRCCS 'Lazzaro Spallanzani' 5XMILLE 2019RICERCA FINALIZZATA 2018 GR-2018-12367178
6 · The paper itself

Abstract

Host-directed therapies are emerging as a promising tool in the curing of difficult-to-treat infections, such as those caused by drug-resistant bacteria. In this study, we aim to test the potential activity of the FDA- and EMA-approved drugs cysteamine and cystamine against

Indexed as

Mycobacterium abscessusMycobacterium Infections, NontuberculousAmikacinAnti-Bacterial AgentsCystamineCysteamineHumansLeukocytes, MononuclearMicrobial Sensitivity TestsAmikacinAnti-Bacterial AgentsCystamineCysteaminecystaminecysteaminehost-directed therapiesMycobacterium abscessustransglutaminase-2

Identifiers

PMID36674717
PMCPMC9866335
OpenAlexW4313891327

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.