ArticleInternational journal of molecular sciences2023
Subacute Ruminal Acidosis as a Potential Factor that Induces Endometrium Injury in Sheep.
Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 23 citations in OpenAlex.
- Physiological Alterations in Local Iraqi Sheep Affected by Ruminal Impaction: Insights from Biochemical, Electrolyte, and Oxidative Markers.F1000Research · 2026Article
- Extracellular vesicles containing microbial DNA contribute to ruminal dysbiosis-induced mastitis by activating cGAS-STING-NF-κB/NLRP3 pathway.Journal of animal science and biotechnology · 2025Article
- Ruminal microbial dysbiosis induces mastitis in dairy goats by activating oxidative stress and ferritinophagy-ferroptosis.iScience · 2025Article
- Altered ruminal microbiome tryptophan metabolism and their derived 3-indoleacetic acid inhibit ruminal inflammation in subacute ruminal acidosis goats.Microbiome · 2025Article
- CcpA-mediated regulation of cellular energy metabolism in the ruminal bacteriumMicrobiology spectrum · 2025Article
- Carbonate Buffer Mixture Alleviates Subacute Rumen Acidosis Induced by Long-Term High-Concentrate Feeding in Dairy Goats by Regulating Rumen Microbiota.Microorganisms · 2025Article
- Integrating Subacute Ruminal Acidosis, Lipopolysaccharide, and Trained Immunity: A Comprehensive Review.International journal of biological sciences · 2025Review
- Study on Rumen Degradability and Intestinal Digestibility of Mutton Sheep Diets with Different Concentrate-to-Forage Ratios and Nonfiber Carbohydrates/Neutral Detergent Fiber Ratios.Animals : an open access journal from MDPI · 2024Article
- Strontium Attenuates LPS-Induced Inflammation via TLR4/MyD88/NF-κB Pathway in Bovine Ruminal Epithelial Cells.Biological trace element research · 2024Article
- Epigallocatechin-3-gallate protects bovine ruminal epithelial cells against lipopolysaccharide-induced inflammatory damage by activating autophagy.Journal of animal science and biotechnology · 2024Article
- Cecropin A Alleviates LPS-Induced Oxidative Stress and Apoptosis of Bovine Endometrial Epithelial Cells.Animals : an open access journal from MDPI · 2024Article
- Disorders of acid-base balance promote rumen lipopolysaccharide biosynthesis in dairy cows by modulating the microbiome.Frontiers in microbiology · 2024Article
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
Abstract
The demand for economic benefits has led to an increase in the proportion of high-concentrate (HC) feed in the ruminant diet, resulting in an increased incidence of subacute ruminal acidosis (SARA). During SARA, a high concentration of lipopolysaccharide (LPS) translocated in the rumen induces a systemic inflammatory response. Inflammatory diseases, such as endometritis and mastitis, are often associated with SARA; however, in sheep, the mechanism of the effect of SARA on the endometrium has rarely been reported. Therefore, the aim of this study was to investigate, for the first time, the influence of LPS translocation on endometrial tight junctions (TJs) during SARA in sheep. The results showed that LPS and TNFα levels in the ruminal fluid, serum, and endometrial tissue supernatant during SARA increased, transcription levels of
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Registered trials
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