Evidence map›Paper›PMID 36674610›Full record

ArticleInternational journal of molecular sciences2023

Curcumin Has Beneficial Effects on Lysosomal Alpha-Galactosidase: Potential Implications for the Cure of Fabry Disease.

Maria Monticelli, Bruno Hay Mele, Mariateresa Allocca, Ludovica Liguori, Jan Lukas, Maria Chiara Monti, Elva Morretta, Maria Vittoria Cubellis, Giuseppina Andreotti

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Maria MonticelliDepartment of Biology, University of Napoli "Federico II", Complesso Universitario Monte Sant'Angelo, Via Cinthia, 80126 Napoli, Italy.ORCID 0000-0003-3136-2138
Bruno Hay MeleDepartment of Biology, University of Napoli "Federico II", Complesso Universitario Monte Sant'Angelo, Via Cinthia, 80126 Napoli, Italy.ORCID 0000-0001-5579-183X
Mariateresa AlloccaInstitute of Biomolecular Chemistry ICB, CNR, Via Campi Flegrei 34, 80078 Pozzuoli, Italy.ORCID 0000-0003-3693-2515
Ludovica LiguoriInstitute of Biomolecular Chemistry ICB, CNR, Via Campi Flegrei 34, 80078 Pozzuoli, Italy.ORCID 0000-0002-8480-0501
Jan LukasTranslational Neurodegeneration Section "Albrecht-Kossel", Department of Neurology, University Medical Center Rostock, 18147 Rostock, Germany.ORCID 0000-0002-8061-5798
Maria Chiara MontiDepartment of Pharmacy, University of Salerno, Via Giovanni Paolo II 132, 84084 Fisciano, Italy.ORCID 0000-0002-1337-2909
Elva MorrettaDepartment of Pharmacy, University of Salerno, Via Giovanni Paolo II 132, 84084 Fisciano, Italy.ORCID 0000-0002-7244-0297
Maria Vittoria CubellisDepartment of Biology, University of Napoli "Federico II", Complesso Universitario Monte Sant'Angelo, Via Cinthia, 80126 Napoli, Italy.ORCID 0000-0001-6147-6553
Giuseppina AndreottiInstitute of Biomolecular Chemistry ICB, CNR, Via Campi Flegrei 34, 80078 Pozzuoli, Italy.ORCID 0000-0002-1594-0156
University of Campania "Luigi Vanvitelli" · ITIstituto Nazionale di Fisica Nucleare, Sezione di Napoli · ITUniversity of Salerno · ITIstituto di Chimica Biomolecolare · ITUniversity of Rostock · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fabry disease is a lysosomal storage disease caused by mutations in the

Indexed as

CurcuminFabry Disease1-Deoxynojirimycinalpha-GalactosidaseGalactoseHumansLysosomesMutation1-Deoxynojirimycinalpha-GalactosidaseCurcuminGalactoseAGALcurcumindrug repositioningFabry diseaselysosomal storage diseasesnutraceuticalpharmacological chaperone

Identifiers

PMID36674610
PMCPMC9863837
OpenAlexW4313647411

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.