Evidence map›Paper›PMID 36674595›Full record

ReviewInternational journal of molecular sciences2023

Skin Cancer Pathobiology at a Glance: A Focus on Imaging Techniques and Their Potential for Improved Diagnosis and Surveillance in Clinical Cohorts.

Elena-Georgiana Dobre, Mihaela Surcel, Carolina Constantin, Mihaela Adriana Ilie, Ana Caruntu, Constantin Caruntu, Monica Neagu

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
11.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 51 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Gels (Basel, Switzerland) · 2025
    Review
  11. Review
  12. Article
  13. Non-invasive infrared thermography for screening, diagnosis and monitoring of skin cancer.Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG · 2025
    Review
  14. Article
  15. Amelanotic Melanoma-Biochemical and Molecular Induction Pathways.International journal of molecular sciences · 2024
    Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 2 countries.

Elena-Georgiana DobreFaculty of Biology, University of Bucharest, Splaiul Independentei 91-95, 050095 Bucharest, Romania.ORCID 0000-0002-6464-381X
Mihaela SurcelImmunology Department, "Victor Babes" National Institute of Pathology, 050096 Bucharest, Romania.ORCID 0000-0001-5163-4378
Carolina ConstantinImmunology Department, "Victor Babes" National Institute of Pathology, 050096 Bucharest, Romania.ORCID 0000-0002-2870-5497
Mihaela Adriana IlieDepartment of Dermatology, Kalmar County Hospital, 391 85 Kalmar, Sweden.
Ana CaruntuDepartment of Oral and Maxillofacial Surgery, "Carol Davila" Central Military Emergency Hospital, 010825 Bucharest, Romania.ORCID 0000-0003-4200-3069
Constantin CaruntuDepartment of Physiology, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.ORCID 0000-0003-4530-7965
Monica NeaguFaculty of Biology, University of Bucharest, Splaiul Independentei 91-95, 050095 Bucharest, Romania.ORCID 0000-0001-9339-2805
Institutul National Victor Babes · ROUniversity of Bucharest · ROCarol Davila University of Medicine and Pharmacy · ROLandstinget i Kalmar län · SETitu Maiorescu University · RO

Funding

Core Program NASR Project PN19.29.01.01Ministerul Cercetării și Inovării PN-III-P2-2.1-PED-2021-2243Ministerul Cercetării și Inovării PN-III-P4- PCE-2021-0549
6 · The paper itself

Abstract

Early diagnosis is essential for completely eradicating skin cancer and maximizing patients' clinical benefits. Emerging optical imaging modalities such as reflectance confocal microscopy (RCM), optical coherence tomography (OCT), magnetic resonance imaging (MRI), near-infrared (NIR) bioimaging, positron emission tomography (PET), and their combinations provide non-invasive imaging data that may help in the early detection of cutaneous tumors and surgical planning. Hence, they seem appropriate for observing dynamic processes such as blood flow, immune cell activation, and tumor energy metabolism, which may be relevant for disease evolution. This review discusses the latest technological and methodological advances in imaging techniques that may be applied for skin cancer detection and monitoring. In the first instance, we will describe the principle and prospective clinical applications of the most commonly used imaging techniques, highlighting the challenges and opportunities of their implementation in the clinical setting. We will also highlight how imaging techniques may complement the molecular and histological approaches in sharpening the non-invasive skin characterization, laying the ground for more personalized approaches in skin cancer patients.

Indexed as

Skin NeoplasmsHumansMagnetic Resonance ImagingMicroscopy, ConfocalPositron-Emission TomographyProspective StudiesTomography, Optical Coherencecutaneous melanomamagnetic resonance imagingoptical coherence tomographypositron emission tomographyreflectance confocal microscopysquamous cell carcinoma

Identifiers

PMID36674595
PMCPMC9866322
OpenAlexW4313647451

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.