Evidence map›Paper›PMID 36674299›Full record

ArticleInternational journal of environmental research and public health2023

Benefits in Cardiac Function from a Remote Exercise Program in Children with Obesity.

Savina Mannarino, Sara Santacesaria, Irene Raso, Massimo Garbin, Andreana Pipolo, Silvia Ghiglia, Gabriele Tarallo, Annalisa De Silvestri, Matteo Vandoni, Daniela Lucini and 6 more

Abstract read
In one paragraph

Article in International journal of environmental research and public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Preventing Metabolic Syndrome in Adolescents Through Exercise.Advances in experimental medicine and biology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Savina MannarinoPediatric Cardiology Unit, Pediatric Department, Buzzi Children's Hospital, 20154 Milan, Italy.
Sara SantacesariaPediatric Cardiology Unit, Pediatric Department, Buzzi Children's Hospital, 20154 Milan, Italy.
Irene RasoPediatric Cardiology Unit, Pediatric Department, Buzzi Children's Hospital, 20154 Milan, Italy.
Massimo GarbinPediatric Cardiology Unit, Pediatric Department, Buzzi Children's Hospital, 20154 Milan, Italy.ORCID 0000-0002-1694-2559
Andreana PipoloPediatric Cardiology Unit, Pediatric Department, Buzzi Children's Hospital, 20154 Milan, Italy.
Silvia GhigliaPediatric Cardiology Unit, Pediatric Department, Buzzi Children's Hospital, 20154 Milan, Italy.
Gabriele TaralloPediatric Cardiology Unit, Pediatric Department, Buzzi Children's Hospital, 20154 Milan, Italy.
Annalisa De SilvestriBiometry & Clinical Epidemiology, Scientific Direction, Fondazione IRCCS Policlinico San Matteo, 27100 Pavia, Italy.ORCID 0000-0003-3128-8441
Matteo VandoniLaboratory of Adapted Motor Activity (LAMA), Department of Public Health, Experimental Medicine and Forensic Science, University of Pavia, 27100 Pavia, Italy.ORCID 0000-0002-3405-9364
Daniela LuciniBIOMETRA Department, University of Milan, 20129 Milan, Italy.ORCID 0000-0003-4845-8988
Vittoria Carnevale PellinoLaboratory of Adapted Motor Activity (LAMA), Department of Public Health, Experimental Medicine and Forensic Science, University of Pavia, 27100 Pavia, Italy.ORCID 0000-0003-2299-6366
Giuseppina BernardelliExercise Medicine Unit, Istituto Auxologico Italiano, IRCCS, 20135 Milan, Italy.
Alessandro GattiLaboratory of Adapted Motor Activity (LAMA), Department of Public Health, Experimental Medicine and Forensic Science, University of Pavia, 27100 Pavia, Italy.ORCID 0000-0001-6628-7938
Virginia RossiPediatric Unit, Pediatric Department, Buzzi Children's Hospital, 20154 Milan, Italy.ORCID 0000-0001-8363-9210
Valeria CalcaterraPediatric Unit, Pediatric Department, Buzzi Children's Hospital, 20154 Milan, Italy.ORCID 0000-0002-2137-5974
Gianvincenzo ZuccottiPediatric Unit, Pediatric Department, Buzzi Children's Hospital, 20154 Milan, Italy.ORCID 0000-0002-2795-9874

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Physical activity (PA) is a crucial factor in preventing and treating obesity and related complications. In this one-arm pre−post longitudinal prospective study, we evaluated the effects of a 12-week online supervised training program on cardiac morphology, function and blood pressure (BP) in children with obesity. The training program consisted of three sessions per week, each lasting 60 min. Advanced echocardiographic imaging (tissue Doppler and longitudinal strain analysis) was used to detect subclinical changes in heart function. Categorical variables were described as counts and percentages; quantitative variables as the mean and standard deviation (SD) as they were normally distributed (Shapiro−Wilks test). Pre−post comparisons were made with a paired t-test. A total of 27/38 (71%) enrolled patients (18M/9F, 11 ± 2 years) completed the training protocol and were considered in the analysis. At baseline, no hypertensive patient was noted; all echocardiographic variables were within the normal range. After training, we observed a significant reduction in BP parameters, including systolic BP values and Z-score, diastolic BP values, centiles and Z-score, and mean arterial pressure (all p < 0.05). Significant variations in echocardiographic interventricular septum (IVSd) thickness (p = 0.011), IVSd Z-score (p = 0.001), left ventricular (LV) end-diastolic diameter (p = 0.045), LV posterior wall thickness Z-score (p = 0.017), and LV global longitudinal strain (p = 0.016) were detected. No differences in LV diastolic function and right ventricular strain were noted. PA plays a decisive role in improving BP control and has benefits on left ventricle systolic function, representing a strategic approach to limit CV risk. Online exercise could be an excellent method of training in children with obesity.

Indexed as

EchocardiographyObesityChildExerciseExercise TherapyHumansProspective StudiesVentricular Function, Leftadolescentscardiac functioncardiac morphologycardiovascular preventionchildrenobesityphysical activityremote exercise

Identifiers

PMID36674299
PMCPMC9861570

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.