Evidence map›Paper›PMID 36674158›Full record

SynthesisInternational journal of environmental research and public health2023

Effectiveness of Blood Flow Restriction on Functionality, Quality of Life and Pain in Patients with Neuromusculoskeletal Pathologies: A Systematic Review.

Álvaro Jesús Reina-Ruiz, Jesús Martínez-Cal, Guadalupe Molina-Torres, Rita-Pilar Romero-Galisteo, Alejandro Galán-Mercant, Elio Carrasco-Vega, Manuel González-Sánchez

Registry-linked trialOpen access · goldAbstract readSystematic Review
In one paragraph

Synthesis in International journal of environmental research and public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07228780 (Impact of Resistance Training With and Without Venous Occlusion on Strength and Function Post Hand Burn), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
4.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07228780 nacompletednot on this mapstarted 2025, after this paper: background citation

Impact of Resistance Training With and Without Venous Occlusion on Strength and Function Post Hand Burn

TypeinterventionalSponsorCairo UniversityRan2025 to 2026Enrolled34ConditionsHand BurnArmsresistance exercise with venous occlusion, traditional resistance exercises
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Trial
  2. Blood Flow Restriction Training in Hemodialysis Patients: Clinical Benefits, Challenges, and Future Perspectives.Hemodialysis international. International Symposium on Home Hemodialysis · 2026
    Review
  3. Review
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Álvaro Jesús Reina-RuizDepartment of Physiotherapy, Faculty of Health Sciences, University of Málaga, 29071 Málaga, Spain.ORCID 0000-0001-6708-8201
Jesús Martínez-CalDepartment of Nursing, Physiotherapy and Medicine, Faculty of Health Sciences, University of Almería, 04120 Almería, Spain.ORCID 0000-0002-2319-1116
Guadalupe Molina-TorresDepartment of Nursing, Physiotherapy and Medicine, Faculty of Health Sciences, University of Almería, 04120 Almería, Spain.ORCID 0000-0002-2261-5482
Rita-Pilar Romero-GalisteoDepartment of Physiotherapy, Faculty of Health Sciences, University of Málaga, 29071 Málaga, Spain.ORCID 0000-0003-4669-0679
Alejandro Galán-MercantInstitute of Biomedicine of Cádiz (INIBICA), 11009 Cádiz, Spain.ORCID 0000-0003-3581-0372
Elio Carrasco-VegaDepartment of Physiotherapy, Faculty of Health Sciences, University of Málaga, 29071 Málaga, Spain.ORCID 0000-0002-6820-6158
Manuel González-SánchezDepartment of Physiotherapy, Faculty of Health Sciences, University of Málaga, 29071 Málaga, Spain.ORCID 0000-0003-3993-5092
Instituto de Investigación Biomédica de Málaga · ESUniversity of Almería · ESUniversidad de Cádiz · ESUniversidad de Málaga · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBlood flow restriction is characterized as a method used during exercise at low loads of around 20-40% of a repetition maximum, or at a low-moderate intensity of aerobic exercise, in which cuffs that occlude the proximal part of the extremities can partially reduce arterial flow and fully restrict the venous flow of the musculature in order to achieve the same benefits as high-load exercise.

objectiveThe main objective of this systematic literature review was to analyze the effects of BFR intervention on pain, functionality, and quality of life in subjects with neuromusculoskeletal pathologies.

methodsThe search to carry out was performed in PubMed, Cochrane, EMBASE, PEDro, CINHAL, SPORTDiscus, Trip Medical Database, and Scopus: "kaatsu" OR "ischemic training" OR "blood flow restriction" OR "occlusion resistance training" OR "vascular occlusion" OR "vascular restriction".

resultsAfter identifying 486 papers and eliminating 175 of them due to duplication and 261 after reading the title and abstract, 50 papers were selected. Of all the selected articles, 28 were excluded for not presenting a score equal to or higher than 6 points on the PEDro scale and 8 for not analyzing the target outcome variables. Finally, 14 papers were selected for this systematic review.

conclusionsThe data collected indicate that the blood flow restriction tool is a therapeutic alternative due to its effectiveness under different exercise modalities. The benefits found include decreases in pain thresholds and improvement in the functionality and quality of life of the neuro-musculoskeletal patient during the first six weeks. However, the results provided by this tool are still not clear for medium- and long-term interventions.

Indexed as

Quality of LifeResistance TrainingExerciseHemodynamicsHumansPainRegional Blood Flowblood flow restrictionexerciseneuromusculoskeletal disorderspainquality of life

Identifiers

PMID36674158
PMCPMC9858892
OpenAlexW4315700388

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.