Evidence map›Paper›PMID 36674038›Full record

ReviewInternational journal of environmental research and public health2023

The Bidirectional Relationship between Pulmonary Tuberculosis and Lung Cancer.

Mădălina Preda, Bogdan Cosmin Tănase, Daniela Luminița Zob, Adelina Silvana Gheorghe, Cristian Virgil Lungulescu, Elena Adriana Dumitrescu, Dana Lucia Stănculeanu, Loredana Sabina Cornelia Manolescu, Oana Popescu, Elmira Ibraim and 1 more

Open access · goldAbstract readReview
In one paragraph

Review in International journal of environmental research and public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
8.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 45 citations in OpenAlex.

  1. Challenges of tuberculosis in cancer patients: insights from two hospitals in Madrid.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
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  3. RBMX2 linkseLife · 2025
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  12. Frontiers in immunology · 2025
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  16. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Mădălina PredaMarius Nasta Institute of Pneumology, 050159 Bucharest, Romania.ORCID 0000-0002-5927-7069
Bogdan Cosmin TănaseDepartment of Thoracic Surgery, Institute of Oncology "Prof. Dr. Al. Trestioreanu" Bucharest, 022328 Bucharest, Romania.
Daniela Luminița ZobDepartment of Medical Oncology II, Institute of Oncology "Prof. Dr. Al. Trestioreanu" Bucharest, 022328 Bucharest, Romania.
Adelina Silvana GheorgheDepartment of Oncology, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.ORCID 0000-0003-3589-799X
Cristian Virgil LungulescuDepartment of Oncology, University of Medicine and Pharmacy Craiova, 200349 Craiova, Romania.
Elena Adriana DumitrescuDepartment of Oncology, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.
Dana Lucia StănculeanuDepartment of Oncology, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.ORCID 0000-0003-3930-2543
Loredana Sabina Cornelia ManolescuMicrobiology, Parasitology and Virology Discipline, Department of Fundamental Sciences, Faculty of Midwives and Nursing, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.ORCID 0000-0001-8694-6195
Oana PopescuMarius Nasta Institute of Pneumology, 050159 Bucharest, Romania.
Elmira IbraimMarius Nasta Institute of Pneumology, 050159 Bucharest, Romania.
Beatrice MahlerMarius Nasta Institute of Pneumology, 050159 Bucharest, Romania.
Carol Davila University of Medicine and Pharmacy · ROInstitutul de Pneumoftiziologie "Marius Nasta" · ROInstitutul Oncologic Bucuresti · ROUniversity of Medicine and Pharmacy of Craiova · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lung cancer and pulmonary tuberculosis are two significant public health problems that continue to take millions of lives each year. They may have similar symptoms and, in some cases, are diagnosed simultaneously or may have a causal relationship. In tuberculosis disease, the chronic inflammation, different produced molecules, genomic changes, and fibrosis are believed to be important factors that may promote carcinogenesis. As a reverse reaction, the development of carcinogenesis and the treatment may induce the reactivation of latent tuberculosis infection. Moreover, the recently used checkpoint inhibitors are a debatable subject since they help treat lung cancer but may lead to the reactivation of pulmonary tuberculosis and checkpoint-induced pneumonitis. Pulmonary rehabilitation is an effective intervention in post-tuberculosis patients and lung cancer patients and should be recommended to improve outcomes in these pathologies.

Indexed as

Latent TuberculosisLung NeoplasmsTuberculosisTuberculosis, PulmonaryCarcinogenesisHumanscarcinogenesisimmune checkpoint inhibitorslung cancertuberculosis

Identifiers

PMID36674038
PMCPMC9859200
OpenAlexW4315648968

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.