Evidence map›Paper›PMID 36673982›Full record

ArticleInternational journal of environmental research and public health2023

Identification of a Novel Gene Signature with DDR and EMT Difunctionalities for Predicting Prognosis, Immune Activity, and Drug Response in Breast Cancer.

Pan Zhang, Quan Li, Yuni Zhang, Qianqian Wang, Junfang Yan, Aihua Shen, Burong Hu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of environmental research and public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Pan ZhangDepartment of Radiation Medicine, School of Public Health and Management, Wenzhou Medical University, Wenzhou 325035, China.
Quan LiDepartment of Radiation Medicine, School of Public Health and Management, Wenzhou Medical University, Wenzhou 325035, China.
Yuni ZhangDepartment of Radiation Medicine, School of Public Health and Management, Wenzhou Medical University, Wenzhou 325035, China.
Qianqian WangDepartment of Radiation Medicine, School of Public Health and Management, Wenzhou Medical University, Wenzhou 325035, China.
Junfang YanDepartment of Radiation Medicine, School of Public Health and Management, Wenzhou Medical University, Wenzhou 325035, China.
Aihua ShenDepartment of Radiation Medicine, School of Public Health and Management, Wenzhou Medical University, Wenzhou 325035, China.
Burong HuDepartment of Radiation Medicine, School of Public Health and Management, Wenzhou Medical University, Wenzhou 325035, China.
Wenzhou Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Breast cancer, with an overall poor clinical prognosis, is one of the most heterogeneous cancers. DNA damage repair (DDR) and epithelial-mesenchymal transition (EMT) have been identified to be associated with cancer's progression. Our study aimed to explore whether genes with both functions play a more crucial role in the prognosis, immune, and therapy response of breast cancer patients. Based on the Cancer Genome Atlas (TCGA) cancer database, we used LASSO regression analysis to identify the six prognostic-related genes with both DDR and EMT functions, including

Indexed as

Breast Neoplasms14-3-3 ProteinsBreastCarrier ProteinsDatabases, FactualDNA RepairEpithelial-Mesenchymal TransitionFemaleHumansProtein Serine-Threonine Kinases14-3-3 ProteinsCarrier ProteinsHIPK2 protein, humanProtein Serine-Threonine KinasesYWHAG protein, humanbreast cancercancer prognostic modelDNA damage repair (DDR)epithelial–mesenchymal transition (EMT)gene signature

Identifiers

PMID36673982
PMCPMC9859620
OpenAlexW4315650743

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.