Evidence map›Paper›PMID 36673754›Full record

ArticleInternational journal of environmental research and public health2023

Implementation of A Year-Long Antimicrobial Stewardship Program in A 227-Bed Community Hospital in Southern Italy.

Giuseppe Davide Albano, Mauro Midiri, Stefania Zerbo, Emanuele Matteini, Giulia Passavanti, Rosario Curcio, Lidia Curreri, Salvatore Albano, Antonina Argo, Marcello Cadelo

Abstract read
In one paragraph

Article in International journal of environmental research and public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Giuseppe Davide AlbanoSection of Legal Medicine, Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties, University of Palermo, 90129 Palermo, Italy.ORCID 0000-0002-9636-572X
Mauro MidiriSection of Legal Medicine, Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties, University of Palermo, 90129 Palermo, Italy.
Stefania ZerboSection of Legal Medicine, Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties, University of Palermo, 90129 Palermo, Italy.
Emanuele MatteiniFondazione Istituto G. Giglio, Contrada Pietra PollastraPisciotto, 90015 Cefalù, Italy.
Giulia PassavantiFondazione Istituto G. Giglio, Contrada Pietra PollastraPisciotto, 90015 Cefalù, Italy.
Rosario CurcioFondazione Istituto G. Giglio, Contrada Pietra PollastraPisciotto, 90015 Cefalù, Italy.
Lidia CurreriFondazione Istituto G. Giglio, Contrada Pietra PollastraPisciotto, 90015 Cefalù, Italy.
Salvatore AlbanoFondazione Istituto G. Giglio, Contrada Pietra PollastraPisciotto, 90015 Cefalù, Italy.
Antonina ArgoSection of Legal Medicine, Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties, University of Palermo, 90129 Palermo, Italy.ORCID 0000-0002-9964-0184
Marcello CadeloFondazione Istituto G. Giglio, Contrada Pietra PollastraPisciotto, 90015 Cefalù, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHealthcare-Acquired Infections (HAIs) are serious healthcare complications affecting hospital stay, in-hospital mortality, and costs. Root cause analysis has identified the inappropriate use of antibiotics as the main causative factor in the expansion of multi-drug-resistant organisms (MDRO) in our hospital. An Antimicrobial Stewardship (AMS) program was implemented to optimize antibiotic use, limit the development of resistance, improve therapeutic efficacy and clinical outcomes, and reduce costs.

methodsThe stewardship strategies were: antimicrobial oversight on "critical" antibiotics; the development of hospital guidelines on antibiotic selection with the production of a consensus document; the implementation of clinical and management control algorithms with visual impact and Business Intelligence methods; training and updating; and the monitoring of outcome measures and process indicators.

resultsClinical outcomes: length of stay reduced by 0.23 days, hospital readmission/first month rates decreased by 19%, and mortality for infections reduced by 8.8%. Microbiological Outcomes:

conclusionsThe systematic application of the AMS program in a small hospital led to multiple improvements in clinical, microbiological, and economic outcome measures. The analysis of the core indicators for our hospital AMS program showed a significant adherence to the model and hospital recommendations.

Indexed as

Antimicrobial StewardshipHospitals, CommunityAnti-Bacterial AgentsGram-Negative BacteriaHumansItalyAnti-Bacterial Agentsantimicrobial stewardship (AMS)healthcare-acquired infections (HAIs)litigationmedico-legal issuesmultidrug-resistant organism (MDRO)patient safetyresponsibility

Identifiers

PMID36673754
PMCPMC9859386

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.