Evidence map›Paper›PMID 36673670›Full record

ReviewInternational journal of environmental research and public health2023

Contribution of Genetic Polymorphisms in Human Health.

Pieranna Chiarella, Pasquale Capone, Renata Sisto

Open access · goldAbstract readReview
In one paragraph

Review in International journal of environmental research and public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
16.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it, 52 citations in OpenAlex.

  1. Meta-analysis ofInternational journal of immunopathology and pharmacology
    Pooled it
  2. Review
  3. Article
  4. Review
  5. Article
  6. International journal of molecular sciences · 2026
    Article
  7. Diseases (Basel, Switzerland) · 2025
    Review
  8. The Role of Functional Polymorphisms of ApoptoticIranian journal of medical sciences · 2025
    Article
  9. Article
  10. Prevalence of risk phenotypes associated withFrontiers in pharmacology · 2025
    Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Pieranna ChiarellaDepartment of Occupational and Environmental Medicine, Epidemiology and Hygiene, INAIL Research, Via Fontana Candida 1, Monteporzio Catone, 00078 Rome, Italy.ORCID 0000-0001-8367-4032
Pasquale CaponeDepartment of Occupational and Environmental Medicine, Epidemiology and Hygiene, INAIL Research, Via Fontana Candida 1, Monteporzio Catone, 00078 Rome, Italy.ORCID 0000-0002-2553-0345
Renata SistoDepartment of Occupational and Environmental Medicine, Epidemiology and Hygiene, INAIL Research, Via Fontana Candida 1, Monteporzio Catone, 00078 Rome, Italy.ORCID 0000-0002-5086-7003
Istituto Nazionale per l'Assicurazione Contro gli Infortuni sul Lavoro · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human health is influenced by various factors; these include genetic inheritance, behavioral lifestyle, socioeconomic and environmental conditions, and public access to care and therapies in case of illness, with the support of the national health system. All these factors represent the starting point for the prevention and promotion of a healthy lifestyle. However, it is not yet clear to what extent these factors may actually affect the health of an entire population. The exposures to environmental and occupational factors are several, most of which might be poorly known, contributing to influencing individual health. Personal habits, including diet, smoking, alcohol, and drug consumption, together with unhealthy behaviors, may inevitably lead people to the development of chronic diseases, contributing to increasing aging and decreasing life expectancy. In this article, we highlight the role of susceptibility biomarkers, i.e., the genetic polymorphisms of individuals of different ethnicities, with particular attention to the risk factors in the response to specific exposures of Europeans. Moreover, we discuss the role of precision medicine which is representing a new way of treating and preventing diseases, taking into account the genetic variability of the individual with each own clinical history and lifestyle.

Indexed as

Life ExpectancyPolymorphism, GeneticDietHumansRisk FactorsSmokingdiseaseenvironmentgenetic variabilityhealthlifestyleprecision medicinerisk factor

Identifiers

PMID36673670
PMCPMC9858723
OpenAlexW4313583472

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.