Evidence map›Paper›PMID 36673654›Full record

ArticleInternational journal of environmental research and public health2023

Sex-Specific Relationships of Physical Activity and Sedentary Behaviour with Oxidative Stress and Inflammatory Markers in Young Adults.

Juan Corral-Pérez, Martin Alcala, Daniel Velázquez-Díaz, Alejandro Perez-Bey, María Á Vázquez-Sánchez, Maria Calderon-Dominguez, Cristina Casals, Jesús G Ponce-González

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Rehydration Beverages Made fromFoods (Basel, Switzerland) · 2025
    Article
  5. Oxidative Stress in Children and Adolescents: Insights Into Human Biology.American journal of human biology : the official journal of the Human Biology Council · 2025
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Juan Corral-PérezExPhy Research Group, Department of Physical Education, Faculty of Education Sciences, University of Cadiz, 11519 Cadiz, Spain.ORCID 0000-0002-6574-9827
Martin AlcalaDepartment of Chemistry and Biochemistry, Facultad de Farmacia, Universidad San Pablo-CEU, CEU Universities, 28003 Madrid, Spain.ORCID 0000-0003-4678-8860
Daniel Velázquez-DíazExPhy Research Group, Department of Physical Education, Faculty of Education Sciences, University of Cadiz, 11519 Cadiz, Spain.ORCID 0000-0001-6270-9208
Alejandro Perez-BeyBiomedical Research and Innovation Institute of Cadiz (INiBICA) Research Unit, Puerta del Mar University Hospital, 11009 Cadiz, Spain.ORCID 0000-0002-9849-5544
María Á Vázquez-SánchezDepartment of Nursing, Faculty of Health Sciences, PASOS Research Group and UMA REDIAS Network of Law and Artificial Intelligence applied to Health and Biotechnology, University of Malaga, 29071 Malaga, Spain.ORCID 0000-0001-7785-5857
Maria Calderon-DominguezBiomedical Research and Innovation Institute of Cadiz (INiBICA) Research Unit, Puerta del Mar University Hospital, 11009 Cadiz, Spain.ORCID 0000-0003-1797-3450
Cristina CasalsExPhy Research Group, Department of Physical Education, Faculty of Education Sciences, University of Cadiz, 11519 Cadiz, Spain.ORCID 0000-0002-6992-0492
Jesús G Ponce-GonzálezExPhy Research Group, Department of Physical Education, Faculty of Education Sciences, University of Cadiz, 11519 Cadiz, Spain.ORCID 0000-0002-5982-7761
Universidad de Cádiz · ESUniversidad de Málaga · ESUniversidad San Pablo CEU · ES

Funding

Biomedical Research and Innovation Institute of Cadiz LI19/21IN-CO09Spanish Ministry of Science and Innovation PID2019-110063RA-I00/AEI/10.13039/501100011033Spanish Ministry of Science and Innovation PID2020-120034RA-I00University of Cádiz PR2016-051University of Cádiz PR2019-054
6 · The paper itself

Abstract

This study aims to analyse sex-specific associations of physical activity and sedentary behaviour with oxidative stress and inflammatory markers in a young-adult population. Sixty participants (21 women, 22.63 ± 4.62 years old) wore a hip accelerometer for 7 consecutive days to estimate their physical activity and sedentarism. Oxidative stress (catalase, superoxide dismutase, glutathione peroxidase, glutathione, malondialdehyde, and advanced oxidation protein products) and inflammatory (tumour necrosis factor-alpha and interleukin-6) markers were measured. Student t-tests and single linear regressions were applied. The women presented higher catalase activity and glutathione concentrations, and lower levels of advanced protein-oxidation products, tumour necrosis factor-alpha, and interleukin-6 than the men (p < 0.05). In the men, longer sedentary time was associated with lower catalase activity (β = −0.315, p = 0.04), and longer sedentary breaks and higher physical-activity expenditures were associated with malondialdehyde (β = −0.308, p = 0.04). Vigorous physical activity was related to inflammatory markers in the women (tumour necrosis factor-alpha, β = 0.437, p = 0.02) and men (interleukin−6, β = 0.528, p < 0.01). In conclusion, the women presented a better redox and inflammatory status than the men; however, oxidative-stress markers were associated with physical activity and sedentary behaviours only in the men. In light of this, women could have better protection against the deleterious effect of sedentarism but a worse adaptation to daily physical activity.

Indexed as

Sedentary BehaviorTumor Necrosis Factor-alphaAccelerometryAdolescentAdultAntioxidantsCatalaseExerciseFemaleGlutathioneHumansInterleukin-6MaleMalondialdehydeOxidative StressYoung AdultAntioxidantsCatalaseGlutathioneInterleukin-6MalondialdehydeTumor Necrosis Factor-alphaaccelerometryantioxidantsgenderinflammationsedentarism

Identifiers

PMID36673654
PMCPMC9859474
OpenAlexW4313584614

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.