Evidence map›Paper›PMID 36673543›Full record

ArticleHealthcare (Basel, Switzerland)2023

Prevalence of Cardio-Embolic Brain Complications in Permanent and Paroxysmal Atrial Fibrillation Patients.

Ciprian Ilie Rosca, Abhinav Sharma, Daniel-Dumitru Nisulescu, Gabriela Otiman, Daniel-Marius Duda-Seiman, Stelian Ioan Morariu, Daniel Florin Lighezan, Nilima Rajpal Kundnani

Open access · goldAbstract read
In one paragraph

Article in Healthcare (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 11 citations in OpenAlex.

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  11. Importance of H-FABP in Early Diagnosis of Acute Myocardial Infarction.International journal of general medicine · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Ciprian Ilie RoscaCentre for Advanced Research in Cardiovascular Pathology and Hemostasis, Victor Babes University of Medicine and Pharmacy, 300041 Timisoara, Romania.
Abhinav SharmaCivil Medical Society Dr Rosca, 307405 Teremia Mare, Romania.ORCID 0000-0002-0865-0054
Daniel-Dumitru NisulescuInstitute of Cardiovascular Diseases, 300310 Timisoara, Romania.
Gabriela OtimanDepartment of Cardiology, Discipline of Internal Medicine, Ambulatory Care, Prevention and CV Rehabilitation, Victor Babes University of Medicine and Pharmacy, 300020 Timisoara, Romania.
Daniel-Marius Duda-SeimanDepartment of Cardiology, Discipline of Internal Medicine, Ambulatory Care, Prevention and CV Rehabilitation, Victor Babes University of Medicine and Pharmacy, 300020 Timisoara, Romania.
Stelian Ioan MorariuDepartment of Occupational Medicine, Vasile Goldis University of Arad Faculty of Medicine, 473223 Arad, Romania.
Daniel Florin LighezanCentre for Advanced Research in Cardiovascular Pathology and Hemostasis, Victor Babes University of Medicine and Pharmacy, 300041 Timisoara, Romania.
Nilima Rajpal KundnaniDepartment of Functional Sciences, Physiology, Centre of Imuno-Physiology and Biotechnologies (CIFBIOTEH), Victor Babes University of Medicine and Pharmacy, 300041 Timisoara, Romania.ORCID 0000-0002-2824-7182
Victor Babeș University of Medicine and Pharmacy Timișoara · ROArad County Clinical Hospital · ROInstitute e-Austria Timisoara · RORomanian Society of Nephrology · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Atrial fibrillation (AF) is the most frequent of all cardiac arrhythmias, with an increasing prevalence in the last 20 years. Cardio-embolic brain complications (CEBC) related to AF often occur or recur, even following appropriate treatment. Method: We conducted a retrospective study and analyzed the presence of stroke, dementia, and Parkinson’s disease (PD) in both paroxysmal and permanent AF patients. The records of 1111 consecutive admitted patients with primary diagnosis of AF at the Municipal Emergency University Hospital, Timisoara, between 2015 and 2016 were examined. Statistical analysis was performed on the patients included in the study based on the inclusion and exclusion criteria. Results: A significant statistical difference was noted among the permanent AF group for stroke (48.75% vs. 26.74%, p < 0.001) and dementia (10.25% vs. 3.86%, p < 0.001) compared to paroxysmal AF patients. Permanent AF patients presented a higher risk of developing stroke, dementia, and PD compared to patients with paroxysmal AF. Meanwhile, male gender and an increase in age showed an increase in the odds of having cardio-embolic brain complications in patients with paroxysmal AF. Conclusion: Based on the results obtained, it can be concluded that the risk of cardio-cerebral embolic complications is greater in permanent AF patients compared to paroxysmal AF cases. Ischemic stroke and dementia are more frequent in the permanent AF group, but analyzing the data regarding the age of onset paroxysmal AF is critical due to the fact that it involves a younger population. Prompt diagnosis and treatment can help significantly in saving stroke patients.

Indexed as

atrial fibrillationcardioembolic brain damagedementiaParkinson’s diseaseparoxysmal AFpermanent AFstroke

Identifiers

PMID36673543
PMCPMC9858915
OpenAlexW4313647021

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.