Evidence map›Paper›PMID 36673344›Full record

ArticleFoods (Basel, Switzerland)2023

Microencapsulation of Probiotics by Oil-in-Water Emulsification Technique Improves Cell Viability under Different Storage Conditions.

Sebastião Ânderson Dantas da Silva, Leonam da Silva Pereira Batista, Dara Souza Diniz, Sara Sayonara da Cruz Nascimento, Neyna Santos Morais, Cristiane Fernandes de Assis, Thaís Souza Passos, Francisco Canindé de Sousa Júnior

Open access · goldAbstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
7.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Probiotic-fortifiedItalian journal of food safety · 2025
    Article
  6. Article
  7. Review
  8. Review
  9. Review
  10. Article
  11. MicroencapsulatedNutrients · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Sebastião Ânderson Dantas da SilvaPostgraduate Program in Nutrition, Health Sciences Center, Federal University of Rio Grande do Norte, Natal 59078-970, RN, Brazil.ORCID 0000-0003-1795-4620
Leonam da Silva Pereira BatistaDepartment of Nutrition, Health Sciences Center, Federal University of Rio Grande do Norte, Natal 59078-970, RN, Brazil.ORCID 0000-0002-4829-4648
Dara Souza DinizDepartment of Pharmacy, Health Sciences Center, Federal University of Rio Grande do Norte, Natal 59012-570, RN, Brazil.
Sara Sayonara da Cruz NascimentoPostgraduate Program in Biotechnology-RENORBIO, Federal University of Rio Grande do Norte, Natal 59078-970, RN, Brazil.ORCID 0000-0002-9419-9027
Neyna Santos MoraisPostgraduate Program in Nutrition, Health Sciences Center, Federal University of Rio Grande do Norte, Natal 59078-970, RN, Brazil.ORCID 0000-0002-6025-3793
Cristiane Fernandes de AssisPostgraduate Program in Nutrition, Health Sciences Center, Federal University of Rio Grande do Norte, Natal 59078-970, RN, Brazil.ORCID 0000-0001-7595-5395
Thaís Souza PassosPostgraduate Program in Nutrition, Health Sciences Center, Federal University of Rio Grande do Norte, Natal 59078-970, RN, Brazil.
Francisco Canindé de Sousa JúniorPostgraduate Program in Nutrition, Health Sciences Center, Federal University of Rio Grande do Norte, Natal 59078-970, RN, Brazil.ORCID 0000-0003-2042-4348
Universidade Federal do Rio Grande do Norte · BR

Funding

Coordenação de Aperfeicoamento de Pessoal de Nível Superior Finance code 001National Council for Scientific and Technological Development 309130/2021-2National Council for Scientific and Technological Development 422405/2016-7
6 · The paper itself

Abstract

Probiotics are associated with health benefits to the host. However, their application can be limited due to a decrease in cell viability during processing, storage, and passage through the gastrointestinal tract. Microencapsulation is a simple and efficient alternative to improve the physical protection and stability of probiotics. The present study aimed to produce and characterize alginate or gelatin-based microparticles containing Lactobacillus acidophilus NRRL B-4495 or Lactiplantibacillus plantarum NRRL B-4496 by oil-in-water (O/W) emulsification and to evaluate the stability under storage conditions. The results showed that L. acidophilus and L. plantarum encapsulated in gelatin (LAEG and LPEG) presented diameters of 26.08 ± 1.74 μm and 21.56 ± 4.17 μm and encapsulation efficiencies of 89.6 ± 4.2% and 81.1 ± 9.7%, respectively. However, those encapsulated in alginate (LAEA and LPEA) showed an encapsulation efficiency of <1.0%. Furthermore, LAEG was stable for 120 days of storage at 5 °C and 25 °C. Therefore, encapsulation in gelatin by O/W emulsification is a promising strategy for protecting and stabilizing probiotic bacteria, enabling future application in foods.

Indexed as

encapsulationLactiplantibacillus plantarumLactobacillus acidophilusporcine gelatinstorage stability

Identifiers

PMID36673344
PMCPMC9857835
OpenAlexW4313646453

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.