Evidence map›Paper›PMID 36673130›Full record

ArticleDiagnostics (Basel, Switzerland)2023

The Role of CRP POC Testing in the Fight against Antibiotic Overuse in European Primary Care: Recommendations from a European Expert Panel.

Ivan Gentile, Nicola Schiano Moriello, Rogier Hopstaken, Carl Llor, Hasse Melbye, Oliver Senn

Abstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Rapid microbiological respiratory point-of-care testing: a qualitative study with primary care clinicians.The British journal of general practice : the journal of the Royal College of General Practitioners · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ivan GentileDepartment of Clinical Medicine and Surgery-Section of Infectious Diseases, University of Naples Federico II, 80131 Naples, Italy.ORCID 0000-0002-5199-8451
Nicola Schiano MorielloNineth Division of Infectious Disease, Cotugno Hospital, 80131 Naples, Italy.ORCID 0000-0001-8474-4776
Rogier HopstakenStar-shl Diagnostic Centers, 3068 Rotterdam, The Netherlands.
Carl LlorDepartment of Public Health and Primary Care, University of Southern Denmark, 5230 Odense, Denmark.
Hasse MelbyeGeneral Practice Research Unit, Department of Community Medicine, The Arctic University of Norway, 6050 Tromsø, Norway.ORCID 0000-0002-9773-3141
Oliver SennInstitute of Primary Care, University of Zurich and University Hospital of Zurich, 8091 Zurich, Switzerland.ORCID 0000-0003-4422-7250

Funding

Abbot Diagnostics not applicable
6 · The paper itself

Abstract

Tackling antibiotic resistance represents one of the major challenges in modern medicine, and limiting antibiotics' overuse represents the first step in this fight. Most antibiotics are prescribed in primary care settings, and lower respiratory tract infections (LRTIs) are one of the most common indications for their prescription. An expert panel conducted an extensive report on C-reactive protein point-of-care (CRP POC) testing in the evaluation of LRTIs and its usefulness to limit antibiotic prescriptions. The expert panel stated that CRP POC testing is a potentially useful tool to limit antibiotic prescriptions for LRTI in a community setting. CRP POC must be used in conjunction with other strategies such as improved communication skills and the use of other molecular POC testing. Potential barriers to the adoption of CRP POC testing are financial and logistical issues. Moreover, the efficacy in limiting antibiotic prescriptions could be hampered by the fact that, in some countries, patients may gain access to antibiotics even without a prescription. Through the realization of a better reimbursement structure, the inclusion in standardized procedures in local guidelines, and better patient education, CRP point-of-care testing can represent a cornerstone in the fight against antimicrobial resistance.

Indexed as

antimicrobial resistanceC-reactive proteinprimary care

Identifiers

PMID36673130
PMCPMC9857389

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.