ReviewDiagnostics (Basel, Switzerland)2023
Ganglion Cell Complex Analysis: Correlations with Retinal Nerve Fiber Layer on Optical Coherence Tomography.
Review in Diagnostics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 23 citations in OpenAlex.
- Article
- Modalities of vision restoration in optic neuropathies and retinal disease.Progress in retinal and eye research · 2026Review
- Vis-OCT Explorer: an open-source software for visible-light optical coherence tomography data processing.Biomedical optics express · 2026Article
- Multimodal AI-based modeling of glaucoma progression: a 3PM-guided approach integrating structural, functional, and vascular patterns.The EPMA journal · 2025Article
- [Progression assessment of glaucoma].Die Ophthalmologie · 2025Review
- Mean total macular volume measurement using optical coherence tomography in already diagnosed primary open angle glaucoma patients.Pakistan journal of medical sciences · 2025Article
- Percentage macular ganglion cell complex and peripapillary retinal nerve fiber layer loss in different stages of glaucoma.Indian journal of ophthalmology · 2025Article
- Macular Pigment Carotenoid Supplementation for the Preservation of Visual Structure and Function Following a Collegiate Rugby Season.Eye and brain · 2025Article
- Interocular symmetry and asymmetry in ocular health and disease.Frontiers in medicine · 2025Review
- Visual recovery in a patient with optic neuropathy secondary to copper deficiency.American journal of ophthalmology case reports · 2024Article
- A SPATIALLY VARYING HIERARCHICAL RANDOM EFFECTS MODEL FOR LONGITUDINAL MACULAR STRUCTURAL DATA IN GLAUCOMA PATIENTS.The annals of applied statistics · 2024Article
- Independent Effects of Blood Pressure on Intraocular Pressure and Retinal Ganglion Cell Degeneration: A Mendelian Randomization Study.Investigative ophthalmology & visual science · 2024Article
- Correlation of contrast sensitivity with ganglion cell/inner plexiform layer thickness and damage location in glaucoma with varying severity.Eye (London, England) · 2024Article
- Non-Neovascular Age-Related Macular Degeneration Assessment: Focus on Optical Coherence Tomography Biomarkers.Diagnostics (Basel, Switzerland) · 2024Review
- Predictive visual field outcomes after optic chiasm decompressive surgery by retinal vessels parameters using optical coherence tomography angiography.International journal of ophthalmology · 2024Article
- The Discriminatory Ability of Ganglion Cell Inner Plexiform Layer Complex Thickness in Patients with Preperimetric Glaucoma.Journal of current ophthalmologyArticle
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this review is to analyze the correlations between the changes in the ganglion cell complex (GCC) and the retinal nerve fiber layer (RNFL) on optical coherence tomography in different possible situations, especially in eyes with glaucoma. For glaucoma evaluation, several studies have suggested that in the early stages, GCC analysis, especially the thickness of the infero and that of the inferotemporal GCC layers, is a more sensitive examination than circumpapillary RNFL (pRNFL). In the moderate stages of glaucoma, inferior pRNFL thinning is better correlated with the disease than in advanced cases. Another strategy for glaucoma detection is to find any asymmetry of the ganglion cell-inner plexiform layers (GCIPL) between the two macular hemifields, because this finding is a valuable indicator for preperimetric glaucoma, better than the RNFL thickness or the absolute thickness parameters of GCIPL. In preperimetric and suspected glaucoma, GCC and pRNFL have better specificity and are superior to the visual field. In advanced stages, pRNFL and later, GCC reach the floor effect. Therefore, in this stage, it is more useful to evaluate the visual field for monitoring the progression of glaucoma. In conclusion, GCC and pRNFL are parameters that can be used for glaucoma diagnosis and monitoring of the progression of the disease, with each having a higher accuracy depending on the stage of the disease.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.