Evidence map›Paper›PMID 36673051›Full record

ArticleDiagnostics (Basel, Switzerland)2023

Successful Detection of the Characteristics of Tear Film Breakup Appearing Immediately after Eye Opening by Videokeratography with a Newly-Developed Indicator.

Norihiko Yokoi, Natsuki Kusada, Hiroaki Kato, Yuki Furusawa, Chie Sotozono, Georgi As Georgiev

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Norihiko YokoiDepartment of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto 602-8566, Japan.
Natsuki KusadaDepartment of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto 602-8566, Japan.
Hiroaki KatoDepartment of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto 602-8566, Japan.
Yuki FurusawaDepartment of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto 602-8566, Japan.
Chie SotozonoDepartment of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto 602-8566, Japan.
Georgi As GeorgievFaculty of Physics, Sofia University "St. Kliment Ohridski", 1164 Sofia, Bulgaria.
Kyoto Prefectural University of Medicine · JPSofia University "St. Kliment Ohridski" · BG

Funding

Japanese Ministry of Education, Culture, Sports, Science and Technology JP16K11269
6 · The paper itself

Abstract

Spot break (SB), a tear film breakup (TFBU) subtype seen in decreased wettability dry eye (DE), is characterized by a spot-like TFBU that appears immediately after eye opening. It is sometimes difficult to detect using currently available devices for evaluating non-invasive TFBU. The purpose of this study was to investigate the effectiveness of using a newly developed videokeratography indicator for detecting SB. The study involved 44 eyes of 44 DE patients (21 eyes with SB (SB group) and 23 eyes with random break in which fluorescein breakup time was ≤ 5 s (s) (RB group)). All eyes were examined using videokeratography, with digital Meyer-ring images being obtained. By calculation of the degree of luminance blur on the cornea in the Meyer-ring images, termed ‘disturbance value’ (DV), DVs at 0 s (DV(0)]), 2 s (DV(2)), and 5 s (DV(5)) after eye opening, and the changes of DV between each time, were compared between the SB and RB groups. Results: No significant differences in DV(2) and DV(5) and the rate of change between DV(2) and DV(5) were found between the two groups. However, DV(0) and rate of change between DV(0) and DV(2) in the SB group were significantly greater (p < 0.001) than those in the RB group. SB characteristics were successfully detected by videokeratography using a new videokeratography DV indicator.

Indexed as

decreased wettability dry eyedisturbance valuespot breaktear film breakup patternvideokeratography

Identifiers

PMID36673051
PMCPMC9858532
OpenAlexW4313894960

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.