Evidence map›Paper›PMID 36672873›Full record

ArticleGenes2023

Identification of Differentially Expressed Genes in the Longissimus Dorsi Muscle of Luchuan and Duroc Pigs by Transcriptome Sequencing.

Pengcheng Pan, Zhaoxian Qin, Wan Xie, Baojian Chen, Zhihui Guan, Bingkun Xie

Open access · goldAbstract read
In one paragraph

Article in Genes, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.4field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Pengcheng PanGuangxi Key Laboratory of Livestock Genetic Improvement, Guangxi Agricultural Vocational and Technical University, Nanning 530001, China.
Zhaoxian QinGuangxi Key Laboratory of Livestock Genetic Improvement, Guangxi Agricultural Vocational and Technical University, Nanning 530001, China.
Wan XieCollege of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, China.
Baojian ChenGuangxi Key Laboratory of Livestock Genetic Improvement, Guangxi Agricultural Vocational and Technical University, Nanning 530001, China.
Zhihui GuanGuangxi Key Laboratory of Livestock Genetic Improvement, Guangxi Agricultural Vocational and Technical University, Nanning 530001, China.
Bingkun XieGuangxi Key Laboratory of Livestock Genetic Improvement, Guangxi Agricultural Vocational and Technical University, Nanning 530001, China.
Nanjing Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Duroc pig originated in the United States and is a typical lean-meat pig. The breed grows fast, and the body size is large, but the meat quality is poor. The Luchuan pig is one of eight excellent local breeds in China; it has tender meat but is small in size. To study the factors that determine growth, we selected the longissimus dorsi muscle of Luchuan and Duroc pigs for transcriptome sequencing. The results of the transcriptome showed that 3682 genes were differentially expressed (DEGs) in the longissimus dorsi muscle of Duroc and Luchuan pigs. We screened out genes related to muscle development and selected the MYL2 (Myosin light chain-2) gene to perform preliminary research. Gene Ontology (GO) enrichment of biological functions and Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis showed that the gene products were mainly involved in the Akt/FoxO signaling pathway, fatty acid metabolism, arachidonic acid metabolism and glycine, serine and threonine metabolism. Such pathways contributed to skeletal muscle growth, fatty acid metabolism and intramuscular fat deposition. These results provide insight into the mechanisms underlying the formation of skeletal muscle and provide candidate genes to improve growth traits, as well as contribute to improving the growth and development traits of pigs through molecular breeding.

Indexed as

Gene Expression ProfilingTranscriptomeAnimalsFatty AcidsMuscle, SkeletalPlant BreedingSwineFatty Acidsgrowth and developmentlongissimus dorsi musclesLuchuan pigmyosin light chain-2 (MYL2/MLC-2)transcriptomics

Identifiers

PMID36672873
PMCPMC9859529
OpenAlexW4313583243

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.