Evidence map›Paper›PMID 36672836›Full record

ArticleGenes2022

FNDC5 Promotes Adipogenic Differentiation of Primary Preadipocytes in Mashen Pigs.

Wei Hei, Ziwei You, Jiaqi An, Tianzhi Zhao, Jiao Li, Wanfeng Zhang, Meng Li, Yang Yang, Pengfei Gao, Guoqing Cao and 3 more

Open access · goldAbstract read
In one paragraph

Article in Genes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Wei HeiCollege of Animal Science, Shanxi Agricultural University, Jinzhong 030801, China.
Ziwei YouCollege of Animal Science, Shanxi Agricultural University, Jinzhong 030801, China.
Jiaqi AnCollege of Animal Science, Shanxi Agricultural University, Jinzhong 030801, China.
Tianzhi ZhaoCollege of Animal Science, Shanxi Agricultural University, Jinzhong 030801, China.
Jiao LiCollege of Animal Science, Shanxi Agricultural University, Jinzhong 030801, China.
Wanfeng ZhangCollege of Animal Science, Shanxi Agricultural University, Jinzhong 030801, China.
Meng LiCollege of Animal Science, Shanxi Agricultural University, Jinzhong 030801, China.
Yang YangCollege of Animal Science, Shanxi Agricultural University, Jinzhong 030801, China.
Pengfei GaoCollege of Animal Science, Shanxi Agricultural University, Jinzhong 030801, China.
Guoqing CaoCollege of Animal Science, Shanxi Agricultural University, Jinzhong 030801, China.
Xiaohong GuoCollege of Animal Science, Shanxi Agricultural University, Jinzhong 030801, China.
Chunbo CaiCollege of Animal Science, Shanxi Agricultural University, Jinzhong 030801, China.
Bugao LiCollege of Animal Science, Shanxi Agricultural University, Jinzhong 030801, China.
Shanxi Agricultural University · CNChinese Academy of Agricultural Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fibronectin type III domain-containing protein 5 (FNDC5) plays an important role in fat deposition, which can be cut to form Irisin to promote fat thermogenesis, resulting in a decrease in fat content. However, the mechanism of FNDC5 related to fat deposition in pigs is still unclear. In this research, we studied the expression of FNDC5 on different adiposes and its function in the adipogenic differentiation of primary preadipocytes in Mashen pigs. The expression pattern of

Indexed as

AdipocytesAdipogenesisAbdominal FatAnimalsFibronectinsSubcutaneous FatSwineTranscription FactorsFibronectinsTranscription Factorsadipogenic differentiationERK1/2FNDC5Mashen pigsprimary preadipocytes

Identifiers

PMID36672836
PMCPMC9858987
OpenAlexW4313328737

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.