Evidence map›Paper›PMID 36672770›Full record

ArticleGenes2022

Polymorphisms in

Cristine Dieter, Leticia de Almeida Brondani, Natália Emerim Lemos, Ariell Freires Schaeffer, Caroline Zanotto, Denise Taurino Ramos, Eliandra Girardi, Felipe Mateus Pellenz, Joiza Lins Camargo, Karla Suzana Moresco and 8 more

Open access · goldAbstract read
In one paragraph

Article in Genes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
3.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.

  1. Pooled it
  2. Frontiers in immunology · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Participation of Single-Nucleotide Variants inPathogens (Basel, Switzerland) · 2023
    Review
  14. Article
  15. TheInternational journal of molecular sciences · 2023
    Article
  16. Review
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 3 institutions in 1 country.

Cristine DieterEndocrine Division, Hospital de Clínicas de Porto Alegre, Porto Alegre 90035-903, RS, Brazil.ORCID 0000-0003-2765-930X
Leticia de Almeida BrondaniEndocrine Division, Hospital de Clínicas de Porto Alegre, Porto Alegre 90035-903, RS, Brazil.
Natália Emerim LemosEndocrine Division, Hospital de Clínicas de Porto Alegre, Porto Alegre 90035-903, RS, Brazil.ORCID 0000-0002-0096-5801
Ariell Freires SchaefferPost-Graduate Program in Medical Sciences, Endocrinology, Department of Internal Medicine, Faculty of Medicine, Universidade Federal do Rio Grande do Sul, Porto Alegre 91501-970, RS, Brazil.
Caroline ZanottoEndocrine Division, Hospital de Clínicas de Porto Alegre, Porto Alegre 90035-903, RS, Brazil.ORCID 0000-0002-8235-7198
Denise Taurino RamosEndocrine Division, Hospital de Clínicas de Porto Alegre, Porto Alegre 90035-903, RS, Brazil.
Eliandra GirardiEndocrine Division, Hospital de Clínicas de Porto Alegre, Porto Alegre 90035-903, RS, Brazil.
Felipe Mateus PellenzEndocrine Division, Hospital de Clínicas de Porto Alegre, Porto Alegre 90035-903, RS, Brazil.ORCID 0000-0002-7829-9407
Joiza Lins CamargoPost-Graduate Program in Medical Sciences, Endocrinology, Department of Internal Medicine, Faculty of Medicine, Universidade Federal do Rio Grande do Sul, Porto Alegre 91501-970, RS, Brazil.ORCID 0000-0001-8834-4075
Karla Suzana MorescoCampus Realeza, Universidade Federal da Fronteira Sul, Realeza 85770-000, PR, Brazil.ORCID 0000-0002-0892-2830
Lucas Lima da SilvaEndocrine Division, Hospital de Clínicas de Porto Alegre, Porto Alegre 90035-903, RS, Brazil.ORCID 0000-0001-6302-8500
Mariana Rauback AubinEndocrine Division, Hospital de Clínicas de Porto Alegre, Porto Alegre 90035-903, RS, Brazil.ORCID 0000-0003-1200-0334
Mayara Souza de OliveiraEndocrine Division, Hospital de Clínicas de Porto Alegre, Porto Alegre 90035-903, RS, Brazil.ORCID 0000-0002-4295-1459
Tatiana Helena RechPost-Graduate Program in Medical Sciences, Endocrinology, Department of Internal Medicine, Faculty of Medicine, Universidade Federal do Rio Grande do Sul, Porto Alegre 91501-970, RS, Brazil.
Luís Henrique CananiEndocrine Division, Hospital de Clínicas de Porto Alegre, Porto Alegre 90035-903, RS, Brazil.
Fernando GerchmanEndocrine Division, Hospital de Clínicas de Porto Alegre, Porto Alegre 90035-903, RS, Brazil.ORCID 0000-0001-5873-9498
Cristiane Bauermann LeitãoEndocrine Division, Hospital de Clínicas de Porto Alegre, Porto Alegre 90035-903, RS, Brazil.
Daisy CrispimEndocrine Division, Hospital de Clínicas de Porto Alegre, Porto Alegre 90035-903, RS, Brazil.
Universidade Federal do Rio Grande do Sul · BRHospital de Clínicas de Porto Alegre · BRUniversidade Federal da Fronteira Sul · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although advanced age, male sex, and some comorbidities impact the clinical course of COVID-19, these factors only partially explain the inter-individual variability in disease severity. Some studies have shown that genetic polymorphisms contribute to COVID-19 severity; however, the results are inconclusive. Thus, we investigated the association between polymorphisms in

Indexed as

COVID-19Disease ProgressionFemaleGenotypeHumansInterferon-Induced Helicase, IFIH1Interferon LambdaInterleukinsMalePolymorphism, GeneticReceptor, Interferon alpha-betaSerine EndopeptidasesTYK2 KinaseIFIH1 protein, humanIFNAR2 protein, humanIFNL4 protein, humanInterferon-Induced Helicase, IFIH1Interferon LambdaInterleukinsReceptor, Interferon alpha-betaSerine EndopeptidasesTMPRSS2 protein, humanTYK2 KinaseTYK2 protein, humanACE1COVID-19IFIH1IFNAR2polymorphismsSARS-CoV-2TMPRSS2TYK2

Identifiers

PMID36672770
PMCPMC9858252
OpenAlexW4312117175

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.