Evidence map›Paper›PMID 36672758›Full record

ArticleGenes2022

Comparison of Marker Effects and Breeding Values at Two Levels at THI for Milk Yield and Quality Traits in Brazilian Holstein Cows.

Eula Regina Carrara, Brayan Dias Dauria, Izally Carvalho Gervásio, Robson Mateus Freitas Silveira, Gregori Alberto Rovadoski, Juliana Petrini, Mayara Salvian, Paulo Fernando Machado, Gerson Barreto Mourão

Abstract read
In one paragraph

Article in Genes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Eula Regina CarraraDepartment of Animal Science, "Luiz de Queiroz" College of Agriculture (ESALQ), University of São Paulo (USP), Piracicaba 13418-900, Brazil.ORCID 0000-0002-3477-6929
Brayan Dias DauriaDepartment of Animal Science, "Luiz de Queiroz" College of Agriculture (ESALQ), University of São Paulo (USP), Piracicaba 13418-900, Brazil.
Izally Carvalho GervásioDepartment of Animal Science, "Luiz de Queiroz" College of Agriculture (ESALQ), University of São Paulo (USP), Piracicaba 13418-900, Brazil.ORCID 0000-0003-3334-6721
Robson Mateus Freitas SilveiraDepartment of Animal Science, "Luiz de Queiroz" College of Agriculture (ESALQ), University of São Paulo (USP), Piracicaba 13418-900, Brazil.ORCID 0000-0003-2285-9695
Gregori Alberto RovadoskiDepartment of Animal Science, "Luiz de Queiroz" College of Agriculture (ESALQ), University of São Paulo (USP), Piracicaba 13418-900, Brazil.ORCID 0000-0003-0306-8839
Juliana PetriniDepartment of Animal Science, "Luiz de Queiroz" College of Agriculture (ESALQ), University of São Paulo (USP), Piracicaba 13418-900, Brazil.
Mayara SalvianDepartment of Animal Science, "Luiz de Queiroz" College of Agriculture (ESALQ), University of São Paulo (USP), Piracicaba 13418-900, Brazil.
Paulo Fernando MachadoDepartment of Animal Science, "Luiz de Queiroz" College of Agriculture (ESALQ), University of São Paulo (USP), Piracicaba 13418-900, Brazil.
Gerson Barreto MourãoDepartment of Animal Science, "Luiz de Queiroz" College of Agriculture (ESALQ), University of São Paulo (USP), Piracicaba 13418-900, Brazil.ORCID 0000-0002-0990-4108

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genomic tools can help in the selection of animals genetically resistant to heat stress, especially the genome-wide association studies (GWAS). The objective of this study was to compare the variance explained by SNPs and direct genomic breeding values (DGVs) at two levels of a temperature and humidity index (THI). Records of milk yield (MY), somatic cell score (SCS), and percentages of casein (CAS), saturated fatty acids (SFA), and unsaturated fatty acids (UFA) in milk from 1157 Holstein cows were used. Traditional breeding values (EBV) were determined in a previous study and used as pseudo-phenotypes. Two levels of THI (heat comfort zone and heat stress zone) were used as environments and were treated as "traits" in a bi-trait model. The GWAS was performed using the genomic best linear unbiased prediction (GBLUP) method. Considering the top 50 SNPs, a total of 36 SNPs were not common between environments, eight of which were located in gene regions related to the evaluated traits. Even for those SNPs that had differences in their explained variances between the two environments, the differences were very small. The animals showed virtually no rank order, with rank correlation values of 0.90, 0.88, 1.00, 0.88, and 0.97 for MY, CAS, SCS, SFA, and UFA, respectively. The small difference between the environments studied can be attributed to the small difference in the pseudo-phenotypes used between the environments, on-farm acclimation, the polygenic nature of the traits, and the THI values studied near the threshold between comfort and heat stress. It is recommended that future studies be conducted with a larger number of animals and at more extreme THI levels.

Indexed as

LactationMilkAnimalsBrazilCaseinsCattleFemaleGenome-Wide Association StudyHot TemperatureHumidityPhenotypeTemperatureCaseinsdairy cattleDBVfatty acidsgenotype-environment interactionheat stressSNP

Identifiers

PMID36672758
PMCPMC9858941

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.