Evidence map›Paper›PMID 36672643›Full record

ArticleBiomedicines2023

Systemic and Airway Epigenetic Disruptions Are Associated with Health Status in COPD.

Ana I Hernandez Cordero, Xuan Li, Chen Xi Yang, Julia Yang, Julia L MacIsaac, Kristy Dever, Michael S Kobor, Stephen Milne, Stephan F van Eeden, Tawimas Shaipanich and 3 more

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Ana I Hernandez CorderoCentre for Heart Lung Innovation, St. Paul's Hospital and University of British Columbia, Vancouver, BC V6Z 1Y6, Canada.
Xuan LiCentre for Heart Lung Innovation, St. Paul's Hospital and University of British Columbia, Vancouver, BC V6Z 1Y6, Canada.
Chen Xi YangCentre for Heart Lung Innovation, St. Paul's Hospital and University of British Columbia, Vancouver, BC V6Z 1Y6, Canada.
Julia YangCentre for Heart Lung Innovation, St. Paul's Hospital and University of British Columbia, Vancouver, BC V6Z 1Y6, Canada.
Julia L MacIsaacEdwin S.H. Leong Healthy Aging Program, Department of Medical Genetics, University of British Columbia, Vancouver, BC V6T 1Z3, Canada.
Kristy DeverEdwin S.H. Leong Healthy Aging Program, Department of Medical Genetics, University of British Columbia, Vancouver, BC V6T 1Z3, Canada.
Michael S KoborEdwin S.H. Leong Healthy Aging Program, Department of Medical Genetics, University of British Columbia, Vancouver, BC V6T 1Z3, Canada.
Stephen MilneCentre for Heart Lung Innovation, St. Paul's Hospital and University of British Columbia, Vancouver, BC V6Z 1Y6, Canada.ORCID 0000-0001-5274-1298
Stephan F van EedenCentre for Heart Lung Innovation, St. Paul's Hospital and University of British Columbia, Vancouver, BC V6Z 1Y6, Canada.ORCID 0000-0002-7224-8852
Tawimas ShaipanichDivision of Respiratory Medicine, Department of Medicine, University of British Columbia, Vancouver, BC V5Z 1M9, Canada.
Stephen LamCentre for Heart Lung Innovation, St. Paul's Hospital and University of British Columbia, Vancouver, BC V6Z 1Y6, Canada.
Janice M LeungCentre for Heart Lung Innovation, St. Paul's Hospital and University of British Columbia, Vancouver, BC V6Z 1Y6, Canada.
Don D SinCentre for Heart Lung Innovation, St. Paul's Hospital and University of British Columbia, Vancouver, BC V6Z 1Y6, Canada.ORCID 0000-0002-0756-6643
University of British Columbia · CABC Cancer Agency · CAThe University of Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epigenetic modifications are common in chronic obstructive pulmonary disease (COPD); however, their clinical relevance is largely unknown. We hypothesized that epigenetic disruptions are associated with symptoms and health status in COPD. We profiled the blood (

Indexed as

airwaybloodCOPDepigeneticsSGRQ

Identifiers

PMID36672643
PMCPMC9855774
OpenAlexW4313558367

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.