Evidence map›Paper›PMID 36672614›Full record

ReviewBiomedicines2022

Genetic Polymorphisms and Diversity in Nonalcoholic Fatty Liver Disease (NAFLD): A Mini Review.

Siti Aishah Sulaiman, Vicneswarry Dorairaj, Muhammad Nafiz Haidi Adrus

Open access · goldAbstract readReview
In one paragraph

Review in Biomedicines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
4.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Genetic Risk of MASLD in Mongolians: Role ofCurrent issues in molecular biology · 2025
    Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Drug design, development and therapy · 2024
    Article
  11. Article
  12. Review
  13. Review
  14. Nutrients · 2023
    Article
  15. Article
  16. Review
  17. Prevalence ofJournal of obesity · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Siti Aishah SulaimanUKM Medical Molecular Biology Institute (UMBI), Universiti Kebangsaan Malaysia (UKM), Jalan Yaa'cob Latiff, Cheras, Kuala Lumpur 56000, Malaysia.ORCID 0000-0001-7309-3381
Vicneswarry DorairajUKM Medical Molecular Biology Institute (UMBI), Universiti Kebangsaan Malaysia (UKM), Jalan Yaa'cob Latiff, Cheras, Kuala Lumpur 56000, Malaysia.ORCID 0000-0003-1377-5633
Muhammad Nafiz Haidi AdrusUKM Medical Molecular Biology Institute (UMBI), Universiti Kebangsaan Malaysia (UKM), Jalan Yaa'cob Latiff, Cheras, Kuala Lumpur 56000, Malaysia.
University Kebangsaan Malaysia Medical Centre · MY

Funding

Fundamental Research Grant Scheme (FRGS) from the Ministry of Higher Education (MOHE), Malaysia FRGS/1/2019/SKK08/UKM/03/8
6 · The paper itself

Abstract

Nonalcoholic fatty liver disease (NAFLD) is a common liver disease with a wide spectrum of liver conditions ranging from hepatic steatosis to nonalcoholic steatohepatitis (NASH), fibrosis, cirrhosis, and hepatocellular carcinoma. The prevalence of NAFLD varies across populations, and different ethnicities have specific risks for the disease. NAFLD is a multi-factorial disease where the genetics, metabolic, and environmental factors interplay and modulate the disease's development and progression. Several genetic polymorphisms have been identified and are associated with the disease risk. This mini-review discussed the NAFLD's genetic polymorphisms and focusing on the differences in the findings between the populations (diversity), including of those reports that did not show any significant association. The challenges of genetic diversity are also summarized. Understanding the genetic contribution of NAFLD will allow for better diagnosis and management explicitly tailored for the various populations.

Indexed as

diversityethnic differencegeneticsNAFLDpolymorphismsteatosis

Identifiers

PMID36672614
PMCPMC9855725
OpenAlexW4313389355

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.