Evidence map›Paper›PMID 36672607›Full record

ReviewBiomedicines2022

Association between Immunosuppressive Therapy Utilized in the Treatment of Autoimmune Disease or Transplant and Cancer Progression.

Amanda Reyes, Atish Mohanty, Rebecca Pharaon, Erminia Massarelli

Open access · goldAbstract readReview
In one paragraph

Review in Biomedicines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Amanda ReyesDepartment of Medical Oncology & Therapeutics Research, City of Hope National Medical Center, Duarte, CA 91010, USA.
Atish MohantyDepartment of Medical Oncology & Therapeutics Research, City of Hope National Medical Center, Duarte, CA 91010, USA.ORCID 0000-0003-1464-3165
Rebecca PharaonDepartment of Medical Oncology & Therapeutics Research, City of Hope National Medical Center, Duarte, CA 91010, USA.
Erminia MassarelliDepartment of Medical Oncology & Therapeutics Research, City of Hope National Medical Center, Duarte, CA 91010, USA.ORCID 0000-0001-7798-7286
City Of Hope National Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autoimmunity and cancer rates have both been on the rise in Western civilization prompting many to investigate the link between the two entities. This review will investigate the complex interactions between the activation and deactivation of the immune system and the development of malignancy. Additional focus will be placed on the main classes of immune inhibitor therapy utilized in transplant patients and in autoimmune disease including TNF-alpha, Calcineurin, mTOR, purine synthesis antagonists and IMPDH inhibitors.

Indexed as

autoimmunitycalcineurin inhibitorscancer progressionimmune checkpoint inhibitorsimmunodeficiencyimmunosurveillanceIMPDH inhibitorsmTOR inhibitorspurine antagonistsTNF-alpha inhibitorstransplant

Identifiers

PMID36672607
PMCPMC9856025
OpenAlexW4313316732

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.