Evidence map›Paper›PMID 36672588›Full record

ReviewBiomedicines2022

The Effects of Transcranial Direct Current Stimulation in Obsessive-Compulsive Disorder Symptoms: A Meta-Analysis and Integrated Electric Fields Modeling Analysis.

Bianca Silva Pinto, Beatriz Araújo Cavendish, Pedro Henrique Rodrigues da Silva, Paulo Jeng Chian Suen, Kalian Almeida Pereira Marinho, Leandro da Costa Lane Valiengo, Marie-Anne Vanderhasselt, André Russowsky Brunoni, Laís Boralli Razza

Open access · goldAbstract readReview
In one paragraph

Review in Biomedicines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Trial
  5. Review
  6. Review
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Bianca Silva PintoServiço Interdisciplinar de Neuromodulação (SIN), Instituto de Psiquiatria do Hospital das Clínicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, São Paulo 05403-903, Brazil.ORCID 0000-0003-3197-4927
Beatriz Araújo CavendishServiço Interdisciplinar de Neuromodulação (SIN), Instituto de Psiquiatria do Hospital das Clínicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, São Paulo 05403-903, Brazil.
Pedro Henrique Rodrigues da SilvaServiço Interdisciplinar de Neuromodulação (SIN), Instituto de Psiquiatria do Hospital das Clínicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, São Paulo 05403-903, Brazil.
Paulo Jeng Chian SuenServiço Interdisciplinar de Neuromodulação (SIN), Instituto de Psiquiatria do Hospital das Clínicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, São Paulo 05403-903, Brazil.ORCID 0000-0002-7806-6603
Kalian Almeida Pereira MarinhoServiço Interdisciplinar de Neuromodulação (SIN), Instituto de Psiquiatria do Hospital das Clínicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, São Paulo 05403-903, Brazil.
Leandro da Costa Lane ValiengoServiço Interdisciplinar de Neuromodulação (SIN), Instituto de Psiquiatria do Hospital das Clínicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, São Paulo 05403-903, Brazil.
Marie-Anne VanderhasseltDepartment of Head and Skin, Psychiatry and Medical Psychology, Ghent University Hospital, Corneel Heymanslaan, 9000 Ghent, Belgium.
André Russowsky BrunoniServiço Interdisciplinar de Neuromodulação (SIN), Instituto de Psiquiatria do Hospital das Clínicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, São Paulo 05403-903, Brazil.
Laís Boralli RazzaServiço Interdisciplinar de Neuromodulação (SIN), Instituto de Psiquiatria do Hospital das Clínicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, São Paulo 05403-903, Brazil.
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo · BRGhent University Hospital · BEUniversidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transcranial direct current stimulation (tDCS) has been showing promising effects for the treatment of obsessive-compulsive disorder (OCD), but there is still no conclusion on its efficacy for this disorder. We performed a systematic review and meta-analysis of trials using tDCS for OCD and a computer modeling analysis to evaluate the electric field (EF) strengths of different electrode assemblies in brain regions of interest (ROIs) (PROSPERO-42021262465). PubMed/MEDLINE, Embase, Cochrane Library and Web of Science databases were searched from inception to 25 September 2022. Randomized controlled trials (RCTs) and open-label studies were included. The primary aim was the effect size (Hedges' g) of continuous outcomes and potential moderators of response. For EF modeling, SimNIBS software was used. Four RCTs and four open-label trials were included (

Indexed as

computer modelingelectric fieldmeta-analysisnoninvasive brain stimulationobsessive–compulsive disorderopen-label trialsrandomized controlled trialsregions of interestsystematic-reviewtranscranial direct current stimulation

Identifiers

PMID36672588
PMCPMC9855366
OpenAlexW4313327314

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.