Evidence map›Paper›PMID 36672548›Full record

ArticleBiomedicines2022

Development and Characterization of a Subcutaneous Implant-Related Infection Model in Mice to Test Novel Antimicrobial Treatment Strategies.

Charlotte Wittmann, Niels Vanvelk, Anton E Fürst, T Fintan Moriarty, Stephan Zeiter

Abstract read
In one paragraph

Article in Biomedicines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Charlotte WittmannAO Research Institute Davos, 7270 Davos, Switzerland.
Niels VanvelkAO Research Institute Davos, 7270 Davos, Switzerland.
Anton E FürstEquine Department-Vetsuisse Faculty, University of Zurich, 8057 Zurich, Switzerland.ORCID 0000-0003-3016-8990
T Fintan MoriartyAO Research Institute Davos, 7270 Davos, Switzerland.ORCID 0000-0003-2307-0397
Stephan ZeiterAO Research Institute Davos, 7270 Davos, Switzerland.ORCID 0000-0002-8155-4202

Funding

AO Foundation AR2020_08
6 · The paper itself

Abstract

Orthopedic-device-related infection is one of the most severe complications in orthopedic surgery. To reduce the associated morbidity and healthcare costs, new prevention and treatment modalities are continuously under development. Preclinical in vivo models serve as a control point prior to clinical implementation. This study presents a mouse model of subcutaneously implanted titanium discs, infected with

Indexed as

biomaterial testingimplant-related infectionmouse model

Identifiers

PMID36672548
PMCPMC9855336

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.