Evidence map›Paper›PMID 36672526›Full record

ArticleBiomedicines2022

Pancreatic Pathological Changes in Murine Toxoplasmosis and Possible Association with Diabetes Mellitus.

Asmaa M El-Kady, Amal M Alzahrani, Hayam Elshazly, Eman Abdullah Alshehri, Majed H Wakid, Hattan S Gattan, Wafa Abdullah I Al-Megrin, Mashael S Alfaifi, Khalil Mohamed, Waheeb Alharbi and 2 more

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 9 institutions in 3 countries.

Asmaa M El-KadyDepartment of Medical Parasitology, Faculty of Medicine, South Valley University, Qena 83523, Egypt.ORCID 0000-0002-9294-2630
Amal M AlzahraniDepartment of Biology, Faculty of Sciences & Arts in Almandaq, Al Baha University, Al Baha 65779, Saudi Arabia.
Hayam ElshazlyDepartment of Biology, Faculty of Sciences-Scientific Departments, Qassim University, Buraidah 52571, Saudi Arabia.ORCID 0000-0002-2892-9271
Eman Abdullah AlshehriDepartment of Zoology, College of Science, King Saud University, Riyadh 11362, Saudi Arabia.
Majed H WakidDepartment of Medical Laboratory Technology, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah 21589, Saudi Arabia.ORCID 0000-0003-4941-5373
Hattan S GattanDepartment of Medical Laboratory Technology, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah 21589, Saudi Arabia.ORCID 0000-0003-3514-4912
Wafa Abdullah I Al-MegrinDepartment of Biology, College of Science, Princess Nourah bint Abdulrahman University, P.O. Box 84428, Riyadh 11671, Saudi Arabia.ORCID 0000-0001-8011-8153
Mashael S AlfaifiDepartment of Epidemiology, Faculty of Public Health and Health Informatics, Umm Al-Qura University, Mecca 21961, Saudi Arabia.ORCID 0000-0001-9563-429X
Khalil MohamedDepartment of Epidemiology, Faculty of Public Health and Health Informatics, Umm Al-Qura University, Mecca 21961, Saudi Arabia.
Waheeb AlharbiDepartment of Physiology, Faculty of Medicine, Umm Al-Qura University, Mecca 21961, Saudi Arabia.
Hatem A ElshabrawyDepartment of Molecular and Cellular Biology, College of Osteopathic Medicine, Sam Houston State University, Conroe, TX 77304, USA.ORCID 0000-0002-7771-113X
Salwa S YounisDepartments of Medical Parasitology, Faculty of Medicine, Alexandria University, Alexandria 21131, Egypt.
Umm al-Qura University · SAKing Abdulaziz University · SAAl Baha University · SAAlexandria University · EGBeni-Suef University · EGKing Saud University · SAPrincess Nourah bint Abdulrahman University · SASam Houston State University · USSouth Valley University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPrevious studies have reported involvement of MATERIALS AND

methodsThree groups (10 mice each) of male Swiss Albino mice were used. One group of mice was left uninfected, whereas the second and third groups were infected with the acute virulent

resultsPancreatic tissues of

conclusionsAcute and chronic toxoplasmosis mice displayed marked pancreatic pathological changes with reduced numbers of islets of Langerhans and insulin-producing-β cells. Since damage of β cells of islets of Langerhans is associated with the development of T1DM, our findings may support a link between

Indexed as

apoptosiscaspase-3CD8diabetesinsulinislets of LangerhansT1DMToxoplasma gondii

Identifiers

PMID36672526
PMCPMC9856159
OpenAlexW4312188148

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.