Evidence map›Paper›PMID 36672457›Full record

ReviewCancers2023

Surgical Strategies for Recurrent Hepatocellular Carcinoma after Resection: A Review of Current Evidence.

Flavio Milana, Michela Anna Polidoro, Simone Famularo, Ana Lleo, Renzo Boldorini, Matteo Donadon, Guido Torzilli

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Benefits and drawbacks of radiofrequency ablationWorld journal of gastrointestinal surgery · 2024
    Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Flavio MilanaDepartment of Biomedical Sciences, Humanitas University, 20072 Pieve Emanuele, MI, Italy.ORCID 0000-0003-3570-9573
Michela Anna PolidoroHepatobiliary Immunopathology Laboratory, IRCCS Humanitas Research Hospital, 20089 Rozzano, MI, Italy.ORCID 0000-0002-9162-6855
Simone FamularoDepartment of Biomedical Sciences, Humanitas University, 20072 Pieve Emanuele, MI, Italy.ORCID 0000-0002-9721-6304
Ana LleoDepartment of Biomedical Sciences, Humanitas University, 20072 Pieve Emanuele, MI, Italy.ORCID 0000-0002-0561-7902
Renzo BoldoriniDepartment of Health Sciences, Università del Piemonte Orientale, 28100 Novara, NO, Italy.
Matteo DonadonHepatobiliary Immunopathology Laboratory, IRCCS Humanitas Research Hospital, 20089 Rozzano, MI, Italy.ORCID 0000-0003-0296-7648
Guido TorzilliDepartment of Biomedical Sciences, Humanitas University, 20072 Pieve Emanuele, MI, Italy.ORCID 0000-0001-5798-5021
Humanitas University · ITUniversità degli Studi del Piemonte Orientale “Amedeo Avogadro” · ITIRCCS Humanitas Research Hospital · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatocellular carcinoma (HCC) is the most common primary liver cancer, and both liver resection and liver transplantation are considered potentially curative options. However, high recurrence rates affect the prognosis depending both on the primary HCC pathology characteristics or on the type and time of the relapse. While great attention has been usually posted on treatment algorithms for the first HCC, treatment algorithms for recurrent HCC (rHCC) are lacking. In these cases, surgery still represents a curative option with both redo hepatectomy and/or salvage liver transplantation, which are considered valid treatments in selected patients. In the current era of personalised medicine with promises of new systemic-targeted immuno-chemotherapies, we wished to perform a narrative review of the literature on the role of surgical strategies for rHCC.

Indexed as

hepatocellular carcinomaliver resectionliver transplantrecurrent hepatocellular carcinomasalvage liver transplantsurgical management

Identifiers

PMID36672457
PMCPMC9856445
OpenAlexW4316467744

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.