ArticleCancers2023
Changing Patterns in Cancer Mortality from 1987 to 2020 in China.
Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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12 citing papers in PubMed, 20 citations in OpenAlex.
- The analysis of the leukemia mortality rate and its temporal trends in China from 2004 to 2021.BMC public health · 2026Article
- Population ageing and gastric cancer mortality burden in China, 2008-2021: a nationwide analysis with projections to 2036.Frontiers in public health · 2026Article
- Economic evaluation of three domestic bevacizumab biosimilars and the original bevacizumab for treating nonsquamous non-small cell lung cancer in china: a cost-effectiveness analysis.Cost effectiveness and resource allocation : C/E · 2025Article
- Roles of LncRNA ARSR in tumor proliferation, drug resistance, and lipid and cholesterol metabolism.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2025Review
- Analysis of trends in cancer mortality and the years of life lost in six provinces in northwest China from 2013 to 2021.Scientific reports · 2025Article
- Early prediction of immunotherapy efficacy for advanced NSCLC based on clinical and pre-treatment contrast-enhanced CT radiomics features.Frontiers in oncology · 2025Article
- Temporal trend in non-melanoma skin cancer mortality in China, 1992-2021: an analysis for the global burden of disease study 2021.Frontiers in medicine · 2025Article
- Epidemiological Evidence That Air Pollutants May Accelerate or Delay Breast Cancer Mortality: A Retrospective Cohort Study.International journal of women's health · 2025Article
- Gender disparities in multi-state health transitions and life expectancy among the ≥50-year-old population: A cross-national multi-cohort study.Journal of global health · 2024Article
- Suicidal ideation in Chinese patients with advanced breast cancer: a multi-center mediation model study.BMC psychology · 2024Article
- Cancer profiles in China and comparisons with the USA: a comprehensive analysis in the incidence, mortality, survival, staging, and attribution to risk factors.Science China. Life sciences · 2024Article
- Age-Period-Cohort Analysis on Long-Term Mortality Trend of Genitourinary Diseases - China, 1987-2021.China CDC weekly · 2023Article
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Authors and funding
9 authors at 2 institutions in 2 countries.
Funding
Abstract
backgroundChina has the highest number of new cancer cases and deaths worldwide, posing huge health and economic burdens to society and affected families. This study comprehensively analyzed secular trends of national cancer mortality statistics to inform future prevention and intervention programs in China.
methodsThe annual estimate of overall cancer mortality and its major subtypes were derived from the National Health Commission (NHC). Joinpoint analysis was used to detect changes in trends, and we used age-period-cohort modeling to estimate cohort and period effects in Cancers between 1987 and 2020. Net drift (overall annual percentage change), local drift (annual percentage change in each age group), longitudinal age curves (expected longitudinal age-specific rate), and period (cohort) relative risks were calculated.
resultsThe age-standardized cancer mortality in urban China has shown a steady downward trend but has not decreased significantly in rural areas. Almost all cancer deaths in urban areas have shown a downward trend, except for colorectal cancer in men. Decreasing mortality from cancers in rural of the stomach, esophagus, liver, leukemia, and nasopharynx was observed, while lung, colorectal cancer female breast, and cervical cancer mortality increased. Birth cohort risks peaked in the cohorts born around 1920-1930 and tended to decline in successive cohorts for most cancers except for leukemia, lung cancer in rural, and breast and cervical cancer in females, whose relative risks were rising in the very recent cohorts. In addition, mortality rates for almost all types of cancer in older Chinese show an upward trend.
conclusionsAlthough the age-standardized overall cancer mortality rate has declined, and the urban-rural gap narrowed, the absolute cancer cases kept increasing due to the growing elderly population in China. The rising mortality related to lung, colorectal, female breast, and cervical cancer should receive higher priority in managing cancer burden and calls for targeted public health actions to reverse the trend.
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