Evidence map›Paper›PMID 36672357›Full record

ArticleCancers2023

Factors Associated with the Breast Cancer Diagnostic Interval across Five Canadian Provinces: A CanIMPACT Retrospective Cohort Study.

Arlinda Ruco, Patti A Groome, Mary L McBride, Kathleen M Decker, Eva Grunfeld, Li Jiang, Cynthia Kendell, Aisha Lofters, Robin Urquhart, Khanh Vu and 1 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 10 institutions in 2 countries.

Arlinda RucoInterdisciplinary Health Program, St. Francis Xavier University, Antigonish, NS B2G 2W5, Canada.ORCID 0000-0002-0221-5836
Patti A GroomeCancer Care and Epidemiology, Queen's Cancer Research Institute, Kingston, ON K7L 3N6, Canada.
Mary L McBrideBritish Columbia Cancer Agency, Vancouver, BC V5Z 4E6, Canada.
Kathleen M DeckerCancerCare Manitoba Research Institute, Winnipeg, MB R3E 0V9, Canada.ORCID 0000-0002-0044-7545
Eva GrunfeldDepartment of Family and Community Medicine, University of Toronto, Toronto, ON M5S 1A1, Canada.
Li JiangOntario Medical Association, Toronto, ON M5S 3C1, Canada.
Cynthia KendellDepartment of Surgery, Dalhousie University and Nova Scotia Health Authority, Halifax, NS B3H 4R2, Canada.
Aisha LoftersWomen's College Hospital, Toronto, ON M5S 1B2, Canada.ORCID 0000-0002-7322-0894
Robin UrquhartDepartment of Surgery, Dalhousie University and Nova Scotia Health Authority, Halifax, NS B3H 4R2, Canada.
Khanh VuSchool of Public Health, University of Alberta, Edmonton, AB T6G 2R3, Canada.
Marcy WingetStanford School of Medicine, Stanford, CA 94305, USA.
Dalhousie University · CABC Cancer Agency · CACancerCare Manitoba · CAOntario Institute for Cancer Research · CAOntario Medical Association · CAQueen's University · CAStanford Medicine · USSt. Francis Xavier University · CAUniversity of Alberta · CAUniversity of Toronto · CA

Funding

CIHR 128272
6 · The paper itself

Abstract

The cancer diagnostic process can be protracted, and it is a time of great anxiety for patients. The objective of this study was to examine inter- and intra-provincial variation in diagnostic intervals and explore factors related to the variation. This was a multi-province retrospective cohort study using linked administrative health databases. All females with a diagnosis of histologically confirmed invasive breast cancer in British Columbia (2007-2010), Manitoba (2007-2011), Ontario (2007-2010), Nova Scotia (2007-2012), and Alberta (2004-2010) were included. The start of the diagnostic interval was determined using algorithms specific to whether the patient's cancer was detected through screening. We used multivariable quantile regression analyses to assess the association between demographic, clinical and healthcare utilization factors with the diagnostic interval outcome. We found significant inter- and intra-provincial variation in the breast cancer diagnostic interval and by screen-detection status; patients who presented symptomatically had longer intervals than screen-detected patients. Interprovincial diagnostic interval variation was 17 and 16 days for screen- and symptom-detected patients, respectively, at the median, and 14 and 41 days, respectively, at the 90th percentile. There was an association of longer diagnostic intervals with increasing comorbid disease in all provinces in non-screen-detected patients but not screen-detected. Longer intervals were observed across most provinces in screen-detected patients living in rural areas. Having a regular primary care provider was not associated with a shorter diagnostic interval. Our results highlight important findings regarding the length of the breast cancer diagnostic interval, its variation within and across provinces, and its association with comorbid disease and rurality. We conclude that diagnostic processes can be context specific, and more attention should be paid to developing tailored processes so that equitable access to a timely diagnosis can be achieved.

Indexed as

breast cancerdiagnostic interval

Identifiers

PMID36672357
PMCPMC9857089
OpenAlexW4313890695

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.