Evidence map›Paper›PMID 36672293›Full record

ArticleCancers2023

A Metabolic Smorgasbord Drives and Sustains CSC Heterogeneity.

Michael Kahn

Abstract readEditorial
In one paragraph

Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Michael KahnDepartment of Cancer Biology and Molecular Medicine, Beckman Research Institute of City of Hope, Duarte, CA 91010, USA.ORCID 0000-0003-1220-4644

Funding

Transgenic Mouse FacilityP30CA033572 · NCI · CITY OF HOPE/BECKMAN RESEARCH INSTITUTE · PI XIWEI WU · 1985 to 2026
$86.3M
Efficacy of Novel Wnt Modulator in Colon CancerR01CA166161 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI KAHN, MICHAEL, LENZ, HEINZ JOSEF · 2013 to 2017
$2.3M
Mechanisms of beta-catenin signaling in alveolar epithelial cell differentiationR01HL112638 · NHLBI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI BOROK, ZEA, KAHN, MICHAEL · 2013 to 2016
$2.2M
Modulation of Wnt Signaling in Models of Multiple SclerosisR21NS074392 · NINDS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI GILMORE, WENDY · 2012 to 2013
$444k
Innate enteric immunity during induced Paneth cell deficiencyR21AI105057 · NIAID · UNIVERSITY OF SOUTHERN CALIFORNIA · PI OUELLETTE, ANDRE J. · 2013 to 2014
$440k
NCI NIH HHS P30 CA033572NCI NIH HHS R01 CA166161NHLBI NIH HHS R01 HL112638NIAID NIH HHS R21 AI105057NINDS NIH HHS R21 NS074392
6 · The paper itself

Abstract

A deeper understanding of the biology of therapy resistance is important for the development of optimal strategies to attain complete cancer cures [...].

Identifiers

PMID36672293
PMCPMC9856803

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.