Evidence map›Paper›PMID 36672274›Full record

ArticleCells2023

The Generation of Human iPSC Lines from Three Individuals with Dravet Syndrome and Characterization of Neural Differentiation Markers in iPSC-Derived Ventral Forebrain Organoid Model.

Valery Zayat, Zuzanna Kuczynska, Michal Liput, Erkan Metin, Sylwia Rzonca-Niewczas, Marta Smyk, Tomasz Mazurczak, Alicja Goszczanska-Ciuchta, Pawel Leszczynski, Dorota Hoffman-Zacharska and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cells, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Valery ZayatDepartment of Stem Cell Bioengineering, Mossakowski Medical Research Institute, Polish Academy of Sciences, 02-106 Warsaw, Poland.
Zuzanna KuczynskaDepartment of Stem Cell Bioengineering, Mossakowski Medical Research Institute, Polish Academy of Sciences, 02-106 Warsaw, Poland.ORCID 0000-0001-8104-9217
Michal LiputDepartment of Stem Cell Bioengineering, Mossakowski Medical Research Institute, Polish Academy of Sciences, 02-106 Warsaw, Poland.
Erkan MetinDepartment of Stem Cell Bioengineering, Mossakowski Medical Research Institute, Polish Academy of Sciences, 02-106 Warsaw, Poland.ORCID 0000-0002-6012-0077
Sylwia Rzonca-NiewczasMedical Genetics Department, Institute of Mother and Child, 01-211 Warsaw, Poland.ORCID 0000-0002-7372-2472
Marta SmykMedical Genetics Department, Institute of Mother and Child, 01-211 Warsaw, Poland.ORCID 0000-0002-7959-044X
Tomasz MazurczakMedical Genetics Department, Institute of Mother and Child, 01-211 Warsaw, Poland.
Alicja Goszczanska-CiuchtaMedical Genetics Department, Institute of Mother and Child, 01-211 Warsaw, Poland.
Pawel LeszczynskiDepartment of Stem Cell Bioengineering, Mossakowski Medical Research Institute, Polish Academy of Sciences, 02-106 Warsaw, Poland.
Dorota Hoffman-ZacharskaMedical Genetics Department, Institute of Mother and Child, 01-211 Warsaw, Poland.ORCID 0000-0001-7367-512X
Leonora BuzanskaDepartment of Stem Cell Bioengineering, Mossakowski Medical Research Institute, Polish Academy of Sciences, 02-106 Warsaw, Poland.ORCID 0000-0003-4433-9906
Mossakowski Medical Research Institute, Polish Academy of Sciences · PLUniversity of Warsaw · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dravet syndrome (DRVT) is a rare form of neurodevelopmental disorder with a high risk of sudden unexpected death in epilepsy (SUDEP), caused mainly (>80% cases) by mutations in the

Indexed as

Epilepsies, MyoclonicInduced Pluripotent Stem CellsHumansNAV1.1 Voltage-Gated Sodium ChannelNeuronsProsencephalonNAV1.1 Voltage-Gated Sodium ChannelDravet syndromeNav1.1 haploinsufficiencyorganoidsPanayiotopoulos syndromeSCN1A-related disordersstem cell reprogramming

Identifiers

PMID36672274
PMCPMC9856691
OpenAlexW4316673365

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.