Evidence map›Paper›PMID 36672094›Full record

ArticleBrain sciences2023

Speech and Nonspeech Parameters in the Clinical Assessment of Dysarthria: A Dimensional Analysis.

Wolfram Ziegler, Theresa Schölderle, Bettina Brendel, Verena Risch, Stefanie Felber, Katharina Ott, Georg Goldenberg, Mathias Vogel, Kai Bötzel, Lena Zettl and 7 more

Open access · goldAbstract read
In one paragraph

Article in Brain sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 8 institutions in 1 country.

Wolfram ZieglerClinical Neuropsychology Research Group (EKN), Institute of Phonetics and Speech Processing, Ludwig-Maximilians-University, 80799 Munich, Germany.ORCID 0000-0002-5760-1232
Theresa SchölderleClinical Neuropsychology Research Group (EKN), Institute of Phonetics and Speech Processing, Ludwig-Maximilians-University, 80799 Munich, Germany.
Bettina BrendelClinic for Psychiatry and Psychotherapy, Neurophysiology & Interventional Neuropsychiatry, University of Tübingen, 72076 Tübingen, Germany.
Verena RischClinical Neuropsychology Research Group (EKN), Institute of Phonetics and Speech Processing, Ludwig-Maximilians-University, 80799 Munich, Germany.
Stefanie FelberClinical Neuropsychology Research Group (EKN), Institute of Phonetics and Speech Processing, Ludwig-Maximilians-University, 80799 Munich, Germany.
Katharina OttDepartment of Neurology, Klinikum Großhadern, Ludwig-Maximilians-University, 81377 Munich, Germany.
Georg GoldenbergClinic for Neuropsychology, City Hospital Munich Bogenhausen, 81925 Munich, Germany.
Mathias VogelClinic for Neuropsychology, City Hospital Munich Bogenhausen, 81925 Munich, Germany.
Kai BötzelDepartment of Neurology, Klinikum Großhadern, Ludwig-Maximilians-University, 81377 Munich, Germany.
Lena ZettlMedical Clinic and Outpatient Clinic IV, Ludwig-Maximilians-University, 81377 Munich, Germany.
Stefan LorenzlClinic for Neurology, Hospital Agatharied, 83734 Hausham, Germany.
Renée LampeSchool of Medicine, Klinikum Rechts der Isar, Orthopedic Department, Research Unit for Pediatric Neuroorthopedics and Cerebral Palsy of the Buhl-Strohmaier Foundation, Technical University of Munich, 81675 Munich, Germany.
Katrin StreckerDepartment of Logopedics, Stiftung ICP Munich, Center for Cerebral Palsy, 81377 Munich, Germany.
Matthis SynofzikDepartment of Neurodegenerative Disease, Hertie-Institute for Clinical Brain Research, German Center for Neurodegenerative Diseases (DZNE), and Center for Neurology, University of Tübingen, 72076 Tübingen, Germany.ORCID 0000-0002-2280-7273
Tobias LindigDepartment of Diagnostic and Interventional Neuroradiology, University Hospital Tübingen, 72076 Tübingen, Germany.
Hermann AckermannDepartment of General Neurology, Hertie-Institute for Clinical Brain Research, University of Tübingen, 72076 Tübingen, Germany.
Anja StaigerClinical Neuropsychology Research Group (EKN), Institute of Phonetics and Speech Processing, Ludwig-Maximilians-University, 80799 Munich, Germany.
Ludwig-Maximilians-Universität München · DEMünchen Klinik Bogenhausen · DEGerman Center for Neurodegenerative Diseases · DEHertie Institute for Clinical Brain Research · DEKrankenhaus Agatharied · DEMunich Cluster for Systems Neurology · DESchön Klinik München Harlaching · DEUniversity of Tübingen · DE

Funding

Deutsche Forschungsgemeinschaft ZI 469/15-1, 15-2, AC 55/10-1
6 · The paper itself

Abstract

Nonspeech (or paraspeech) parameters are widely used in clinical assessment of speech impairment in persons with dysarthria (PWD). Virtually every standard clinical instrument used in dysarthria diagnostics includes nonspeech parameters, often in considerable numbers. While theoretical considerations have challenged the validity of these measures as markers of speech impairment, only a few studies have directly examined their relationship to speech parameters on a broader scale. This study was designed to investigate how nonspeech parameters commonly used in clinical dysarthria assessment relate to speech characteristics of dysarthria in individuals with movement disorders. Maximum syllable repetition rates, accuracies, and rates of isolated and repetitive nonspeech oral-facial movements and maximum phonation times were compared with auditory-perceptual and acoustic speech parameters. Overall, 23 diagnostic parameters were assessed in a sample of 130 patients with movement disorders of six etiologies. Each variable was standardized for its distribution and for age and sex effects in 130 neurotypical speakers. Exploratory Graph Analysis (EGA) and Confirmatory Factor Analysis (CFA) were used to examine the factor structure underlying the diagnostic parameters. In the first analysis, we tested the hypothesis that nonspeech parameters combine with speech parameters within diagnostic dimensions representing domain-general motor control principles. In a second analysis, we tested the more specific hypotheses that diagnostic parameters split along effector (lip vs. tongue) or functional (speed vs. accuracy) rather than task boundaries. Our findings contradict the view that nonspeech parameters currently used in dysarthria diagnostics are congruent with diagnostic measures of speech characteristics in PWD.

Indexed as

clinical diagnosticsDDKdiadochokinesisdysarthria assessmentnonspeech tasksspeech disordersvalidation

Identifiers

PMID36672094
PMCPMC9856358
OpenAlexW4313826088

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.